Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.800 strong 0.977 43 12 2000 2019
Entrez Id: 9839
Gene Symbol: ZEB2
ZEB2 		O60315 zinc finger E-box binding homeobox 2 Transcription factor 292 0.471 0.808 1.00 0.400 strong 1.000 23 1 2005 2019
Entrez Id: 4311
Gene Symbol: MME
MME 		P08473 membrane metalloendopeptidase Enzyme 470 0.407 0.808 1.5E-18 0.300 None 1.000 1 0 2003 2003
Entrez Id: 58484
Gene Symbol: NLRC4
NLRC4 		Q9NPP4 NLR family CARD domain containing 4 145 0.556 0.769 9.9E-12 0.300 None 0 0
Entrez Id: 5336
Gene Symbol: PLCG2
PLCG2 		P16885 phospholipase C gamma 2 Enzyme 82 0.588 0.808 1.00 0.300 None 0 0
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 10 0 2004 2018
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.050 None 1.000 5 0 2004 2014
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.030 None 1.000 3 0 2007 2012
Entrez Id: 4210
Gene Symbol: MEFV
MEFV 		O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.030 None 1.000 3 1 2000 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.030 None 1.000 3 0 2003 2012
Entrez Id: 9351
Gene Symbol: SLC9A3R2
SLC9A3R2 		Q15599 SLC9A3 regulator 2 83 0.588 0.654 3.8E-02 0.020 None 1.000 2 0 2005 2006
Entrez Id: 9169
Gene Symbol: SCAF11
SCAF11 		Q99590 SR-related CTD associated factor 11 77 0.584 0.731 1.00 0.020 None 1.000 2 0 2005 2006
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.020 None 1.000 2 1 2000 2003
Entrez Id: 1822
Gene Symbol: ATN1
ATN1 		P54259 atrophin 1 499 0.409 0.885 1.00 0.020 None 1.000 2 0 2003 2017
Entrez Id: 8487
Gene Symbol: GEMIN2
GEMIN2 		O14893 gem nuclear organelle associated protein 2 Nucleic acid binding 71 0.597 0.654 1.5E-06 0.020 None 1.000 2 0 2005 2006
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2 		Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 555 0.393 0.923 8.0E-03 0.010 None 1.000 1 0 2005 2005
Entrez Id: 8809
Gene Symbol: IL18R1
IL18R1 		Q13478 interleukin 18 receptor 1 Receptor 234 0.473 0.808 8.6E-06 0.010 None 1.000 1 1 2011 2011
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14 		Q16539 mitogen-activated protein kinase 14 Kinase 626 0.379 0.923 0.37 0.010 None 1.000 1 0 2005 2005
Entrez Id: 91662
Gene Symbol: NLRP12
NLRP12 		P59046 NLR family pyrin domain containing 12 95 0.569 0.846 3.6E-28 0.010 None 1.000 1 0 2018 2018
Entrez Id: 9402
Gene Symbol: GRAP2
GRAP2 		O75791 GRB2 related adaptor protein 2 538 0.394 0.923 1.5E-04 0.010 None 1.000 1 0 2005 2005
Entrez Id: 695
Gene Symbol: BTK
BTK 		Q06187 Bruton tyrosine kinase Kinase 290 0.464 0.808 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 64127
Gene Symbol: NOD2
NOD2 		Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.010 None 1.000 1 0 2009 2009
Entrez Id: 5979
Gene Symbol: RET
RET 		P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.010 None 1.000 1 0 2006 2006
Entrez Id: 25897
Gene Symbol: RNF19A
RNF19A 		Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 523 0.397 0.923 2.5E-02 0.010 None 1.000 1 0 2005 2005
Entrez Id: 26073
Gene Symbol: POLDIP2
POLDIP2 		Q9Y2S7 DNA polymerase delta interacting protein 2 530 0.396 0.923 0.41 0.010 None 1.000 1 0 2005 2005