Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.030 None 1.000 3 0 2017 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.010 None 1.000 1 0 1992 1992
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
P09038 fibroblast growth factor 2 Signaling 635 0.383 0.923 1.8E-02 0.010 None 1.000 1 0 1996 1996
Entrez Id: 5340
Gene Symbol: PLG
PLG
P00747 plasminogen Enzyme 586 0.389 0.923 1.0E-02 0.010 None 1.000 1 0 1992 1992
Entrez Id: 3342
Gene Symbol: HTC2
HTC2
hypertrichosis 2 (generalized, congenital) 511 0.392 0.808 0.010 None 1.000 1 0 2005 2005
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.020 None 1.000 2 0 1997 2006
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
P29475 nitric oxide synthase 1 521 0.408 0.885 1.00 0.020 None 1.000 2 0 2018 2018
Entrez Id: 1822
Gene Symbol: ATN1
ATN1
P54259 atrophin 1 499 0.409 0.885 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.060 None 1.000 6 0 2005 2019
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
P42772 cyclin dependent kinase inhibitor 2B 440 0.417 0.769 7.3E-03 0.010 None 1.000 1 0 1996 1996
Entrez Id: 2321
Gene Symbol: FLT1
FLT1
P17948 fms related receptor tyrosine kinase 1 Kinase 424 0.419 0.846 1.00 0.010 None 1.000 1 0 1998 1998
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
P14136 glial fibrillary acidic protein 447 0.421 0.885 1.5E-06 0.040 None 1.000 4 0 1994 2012
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1 399 0.424 0.808 2.6E-12 0.400 None 1.000 31 1 2010 2020
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
Q9Y251 heparanase Enzyme 393 0.425 0.808 2.3E-14 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
P63000 Rac family small GTPase 1 Enzyme modulator 415 0.429 0.962 0.76 0.010 None 1.000 1 0 2002 2002
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
Q99988 growth differentiation factor 15 Signaling 389 0.429 0.808 3.0E-07 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
P46013 marker of proliferation Ki-67 351 0.431 0.808 1.3E-28 0.020 None 1.000 2 0 2003 2009
Entrez Id: 3371
Gene Symbol: TNC
TNC
P24821 tenascin C 369 0.433 0.846 1.3E-07 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2 380 0.434 0.808 0.88 0.400 None 1.000 13 2 2010 2019
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.300 None 1.000 1 0 2009 2009
Entrez Id: 3956
Gene Symbol: LGALS1
LGALS1
P09382 galectin 1 Signaling 362 0.435 0.846 4.5E-03 0.010 None 1.000 1 0 2009 2009
Entrez Id: 57534
Gene Symbol: MIB1
MIB1
Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 329 0.438 0.769 3.4E-88 0.020 None 1.000 2 0 2003 2009
Entrez Id: 3339
Gene Symbol: HSPG2
HSPG2
P98160 heparan sulfate proteoglycan 2 Enzyme modulator 405 0.438 0.885 1.0E-19 0.010 None 1.000 1 0 2018 2018