Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.700 0.971 37 4 1994 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.600 0.971 104 2 1991 2018
Entrez Id: 51741
Gene Symbol: WWOX
WWOX
Q9NZC7 WW domain containing oxidoreductase oxidoreductase 214 0.489 0.655 7.0E-16 0.530 1.000 4 1 2002 2015
Entrez Id: 51196
Gene Symbol: PLCE1
PLCE1
Q9P212 phospholipase C epsilon 1 calcium-binding protein; enzyme modulator; hydrolase; signaling molecule 70 0.616 0.517 4.2E-10 0.500 0.944 19 6 2010 2016
Entrez Id: 7403
Gene Symbol: KDM6A
KDM6A
O15550 lysine demethylase 6A transcription factor 175 0.543 0.724 1.00 0.500 1 0 2014 2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.410 1.000 2 1 2007 2015
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.400 0.947 39 2 1994 2016
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.400 0.939 34 2 1996 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 1.000 28 1 2000 2016
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
P05091 aldehyde dehydrogenase 2 family member oxidoreductase 236 0.481 0.862 2.5E-09 0.400 1.000 22 1 1996 2018
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
P00325 alcohol dehydrogenase 1B (class I), beta polypeptide oxidoreductase 152 0.525 0.759 1.1E-06 0.400 1.000 16 1 1998 2015
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box 2 transcription factor 251 0.459 0.759 0.73 0.400 1.000 10 0 2009 2017
Entrez Id: 482
Gene Symbol: ATP1B2
ATP1B2
P14415 ATPase Na+/K+ transporting subunit beta 2 transporter 14 0.752 0.207 8.2E-02 0.400 1 1 2015 2015
Entrez Id: 340061
Gene Symbol: TMEM173
TMEM173
Q86WV6 transmembrane protein 173 78 0.616 0.621 1.2E-03 0.400 1 1 2015 2015
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 293 0.438 0.759 1.1E-07 0.390 1.000 10 2 2003 2015
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 264 0.449 0.828 4.8E-09 0.390 1.000 9 4 2002 2016
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 369 0.415 0.724 2.1E-03 0.380 1.000 9 3 1998 2017
Entrez Id: 113278
Gene Symbol: SLC52A3
SLC52A3
Q9NQ40 solute carrier family 52 member 3 receptor 79 0.656 0.448 1.9E-02 0.380 1.000 8 1 2010 2016
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha nucleic acid binding; transcription factor 586 0.367 0.793 0.97 0.370 0.857 7 0 2005 2016
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 cytoskeletal protein; hydrolase; nucleic acid binding; transcription factor 376 0.420 0.862 3.5E-03 0.360 0.833 7 0 2014 2017
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.350 0.800 6 0 2012 2016
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 356 0.419 0.862 1.3E-04 0.350 0.800 5 0 2005 2015
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 129 0.519 0.724 0.350 0.800 5 0 2015 2018
Entrez Id: 811
Gene Symbol: CALR
CALR
P27797 calreticulin calcium-binding protein 196 0.492 0.793 0.90 0.340 1.000 5 0 2009 2015
Entrez Id: 25800
Gene Symbol: SLC39A6
SLC39A6
Q13433 solute carrier family 39 member 6 transporter 30 0.672 0.379 2.6E-06 0.340 1.000 4 2 2013 2017