Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
P07099 epoxide hydrolase 1 196 0.500 0.846 3.2E-09 0.010 None < 0.001 1 0 2012 2012
Entrez Id: 7161
Gene Symbol: TP73
TP73
O15350 tumor protein p73 Transcription factor 300 0.449 0.808 1.00 0.010 None < 0.001 1 0 2001 2001
Entrez Id: 83478
Gene Symbol: ARHGAP24
ARHGAP24
Q8N264 Rho GTPase activating protein 24 273 0.456 0.808 3.9E-10 0.010 None < 0.001 1 0 2001 2001
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.020 None 0.500 2 0 2001 2017
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
P17936 insulin like growth factor binding protein 3 Enzyme modulator 350 0.439 0.808 0.91 0.020 None 0.500 2 0 2007 2007
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.030 None 0.667 3 0 2009 2010
Entrez Id: 151306
Gene Symbol: GPBAR1
GPBAR1
Q8TDU6 G protein-coupled bile acid receptor 1 G-protein coupled receptor 122 0.548 0.731 1.4E-09 0.030 None 0.667 3 0 2010 2017
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.030 None 0.667 3 0 2007 2012
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.030 None 0.667 3 2 2011 2014
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.030 None 0.667 3 0 2004 2018
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.040 None 0.750 4 1 1999 2013
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.320 None 0.750 4 0 1996 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.040 None 0.750 4 1 2006 2016
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.070 None 0.857 7 0 2000 2013
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.070 None 0.857 7 0 2016 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 0.958 24 0 2000 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.400 None 0.977 44 4 1994 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 1.000 34 0 1999 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.400 None 1.000 14 5 1997 2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.100 None 1.000 13 0 2000 2019
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 703 0.368 0.962 0.100 None 1.000 13 0 2000 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 1.000 11 0 2006 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.100 None 1.000 10 0 2005 2019
Entrez Id: 79400
Gene Symbol: NOX5
NOX5
Q96PH1 NADPH oxidase 5 57 0.631 0.538 3.0E-28 0.100 None 1.000 10 0 2006 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.090 None 1.000 9 0 1999 2015