Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.897 29 1 1991 2018
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1 399 0.424 0.808 2.6E-12 0.100 None 1.000 25 1 2009 2019
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2 380 0.434 0.808 0.88 0.100 None 1.000 10 1 2009 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.070 None 1.000 7 0 2001 2015
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.040 None 1.000 4 0 2007 2015
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.030 None 1.000 3 0 1998 2008
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
P46013 marker of proliferation Ki-67 351 0.431 0.808 1.3E-28 0.030 None 1.000 3 0 1997 2005
Entrez Id: 57534
Gene Symbol: MIB1
MIB1
Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 329 0.438 0.769 3.4E-88 0.030 None 1.000 3 0 1997 2005
Entrez Id: 3021
Gene Symbol: H3-3B
H3-3B
P84243 H3.3 histone B 77 0.599 0.385 0.81 0.020 None 1.000 2 0 2013 2016
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.020 None 1.000 2 0 2013 2015
Entrez Id: 54840
Gene Symbol: APTX
APTX
Q7Z2E3 aprataxin Nucleic acid binding 94 0.590 0.500 4.0E-10 0.020 None 1.000 2 0 2009 2013
Entrez Id: 3020
Gene Symbol: H3-3A
H3-3A
P84243 H3.3 histone A 134 0.559 0.692 0.12 0.020 None 1.000 2 0 2013 2016
Entrez Id: 7161
Gene Symbol: TP73
TP73
O15350 tumor protein p73 Transcription factor 300 0.449 0.808 1.00 0.020 None 1.000 2 0 2009 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.020 None 1.000 2 0 2003 2009
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
P52926 high mobility group AT-hook 2 Nucleic acid binding 382 0.429 0.808 0.87 0.020 None 1.000 2 0 2014 2015
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.020 None 1.000 2 0 2000 2011
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7
O14733 mitogen-activated protein kinase kinase 7 Kinase 408 0.419 0.808 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 55536
Gene Symbol: CDCA7L
CDCA7L
Q96GN5 cell division cycle associated 7 like 32 0.686 0.615 1.8E-04 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4133
Gene Symbol: MAP2
MAP2
P11137 microtubule associated protein 2 126 0.537 0.692 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 546
Gene Symbol: ATRX
ATRX
P46100 ATRX chromatin remodeler 412 0.452 0.808 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 321 0.459 0.808 8.9E-10 0.010 None 1.000 1 1 2010 2010
Entrez Id: 51074
Gene Symbol: APIP
APIP
Q96GX9 APAF1 interacting protein 23 0.705 0.346 2.7E-11 0.010 None 1.000 1 0 2013 2013
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.010 None 1.000 1 0 1997 1997
Entrez Id: 5052
Gene Symbol: PRDX1
PRDX1
Q06830 peroxiredoxin 1 Enzyme 237 0.485 0.846 7.7E-10 0.010 None 1.000 1 0 2013 2013
Entrez Id: 429
Gene Symbol: ASCL1
ASCL1
P50553 achaete-scute family bHLH transcription factor 1 Transcription factor 136 0.552 0.692 0.68 0.010 None 1.000 1 0 2005 2005