Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.240 None 1.000 5 0 1994 2010
Entrez Id: 29
Gene Symbol: ABR
ABR
Q12979 ABR activator of RhoGEF and GTPase Enzyme modulator 46 0.650 0.500 0.63 0.010 None 1.000 1 0 1995 1995
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.010 None 1.000 1 0 1995 1995
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.010 None 1.000 1 0 1997 1997
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.010 None 1.000 1 0 2001 2001
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.300 None 1.000 1 0 2001 2001
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.300 None 1.000 1 0 2001 2001
Entrez Id: 10397
Gene Symbol: NDRG1
NDRG1
Q92597 N-myc downstream regulated 1 Enzyme 225 0.488 0.731 1.1E-02 0.300 None 1.000 1 0 2004 2004
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.300 None 1.000 1 0 2004 2004
Entrez Id: 4155
Gene Symbol: MBP
MBP
P02686 myelin basic protein 184 0.510 0.885 0.28 0.010 None 1.000 1 0 2005 2005
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.010 None 1.000 1 0 2006 2006
Entrez Id: 26524
Gene Symbol: LATS2
LATS2
Q9NRM7 large tumor suppressor kinase 2 Kinase 106 0.554 0.654 0.99 0.300 None 1.000 1 0 2006 2006
Entrez Id: 9113
Gene Symbol: LATS1
LATS1
O95835 large tumor suppressor kinase 1 Kinase 99 0.563 0.731 1.00 0.300 None 1.000 1 0 2006 2006
Entrez Id: 27352
Gene Symbol: SGSM3
SGSM3
Q96HU1 small G protein signaling modulator 3 Enzyme 259 0.469 0.808 3.4E-15 0.010 None 1.000 1 0 2009 2009
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.310 None 1.000 2 2 2010 2013
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.300 None 1.000 2 0 2010 2013
Entrez Id: 10683
Gene Symbol: DLL3
DLL3
Q9NYJ7 delta like canonical Notch ligand 3 134 0.552 0.654 5.4E-05 0.300 None 1.000 1 0 2010 2010
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
Q04721 notch receptor 2 384 0.441 0.808 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.300 None 1.000 1 0 2010 2010
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.300 None 1.000 1 0 2010 2010
Entrez Id: 23462
Gene Symbol: HEY1
HEY1
Q9Y5J3 hes related family bHLH transcription factor with YRPW motif 1 Transcription factor 110 0.551 0.692 5.0E-02 0.300 None 1.000 1 0 2010 2010
Entrez Id: 23493
Gene Symbol: HEY2
HEY2
Q9UBP5 hes related family bHLH transcription factor with YRPW motif 2 Transcription factor 93 0.572 0.731 0.89 0.300 None 1.000 1 0 2010 2010
Entrez Id: 3791
Gene Symbol: KDR
KDR
P35968 kinase insert domain receptor Kinase 623 0.378 0.885 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.010 None 1.000 1 0 2010 2010