Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.300 None 0.867 15 1 1991 2011
Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB
P09619 platelet derived growth factor receptor beta Kinase 492 0.416 0.846 0.90 0.010 None 1.000 1 0 1992 1992
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.050 None 1.000 5 0 1996 2014
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.010 None 1.000 1 0 1996 1996
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
P49815 TSC complex subunit 2 Enzyme modulator 410 0.439 0.808 1.00 0.010 None 1.000 1 0 1997 1997
Entrez Id: 7012
Gene Symbol: TERC
TERC
telomerase RNA component 296 0.471 0.846 0.010 None 1.000 1 0 1997 1997
Entrez Id: 2113
Gene Symbol: ETS1
ETS1
P14921 ETS proto-oncogene 1, transcription factor Transcription factor 327 0.444 0.731 0.78 0.010 None 1.000 1 0 1999 1999
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.020 None 0.500 2 0 2001 2016
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.300 None 1.000 1 0 2001 2001
Entrez Id: 6855
Gene Symbol: SYP
SYP
P08247 synaptophysin Transporter 243 0.481 0.808 0.92 0.010 None 1.000 1 0 2001 2001
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.010 None 1.000 1 0 2001 2001
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.300 None 1.000 1 0 2001 2001
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
P22455 fibroblast growth factor receptor 4 Kinase 220 0.490 0.769 7.2E-13 0.010 None < 0.001 1 0 2002 2002
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.040 None 1.000 4 0 2003 2015
Entrez Id: 818
Gene Symbol: CAMK2G
CAMK2G
Q13555 calcium/calmodulin dependent protein kinase II gamma Kinase 51 0.670 0.462 1.00 0.010 None 1.000 1 0 2003 2003
Entrez Id: 1755
Gene Symbol: DMBT1
DMBT1
Q9UGM3 deleted in malignant brain tumors 1 Enzyme 135 0.533 0.654 4.5E-63 0.010 None 1.000 1 0 2004 2004
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.300 None 1.000 1 0 2004 2004
Entrez Id: 10397
Gene Symbol: NDRG1
NDRG1
Q92597 N-myc downstream regulated 1 Enzyme 225 0.488 0.731 1.1E-02 0.300 None 1.000 1 0 2004 2004
Entrez Id: 8745
Gene Symbol: ADAM23
ADAM23
O75077 ADAM metallopeptidase domain 23 Enzyme 49 0.650 0.500 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 26524
Gene Symbol: LATS2
LATS2
Q9NRM7 large tumor suppressor kinase 2 Kinase 106 0.554 0.654 0.99 0.300 None 1.000 1 0 2006 2006
Entrez Id: 9113
Gene Symbol: LATS1
LATS1
O95835 large tumor suppressor kinase 1 Kinase 99 0.563 0.731 1.00 0.300 None 1.000 1 0 2006 2006
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.330 None 1.000 4 2 2009 2016
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.010 None 1.000 1 1 2009 2009
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.010 None 1.000 1 0 2009 2009
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.010 None 1.000 1 0 2009 2009