Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.040 None 1.000 4 0 2003 2017
Entrez Id: 5653
Gene Symbol: KLK6
KLK6
Q92876 kallikrein related peptidase 6 Enzyme 99 0.575 0.654 6.0E-03 0.040 None 1.000 4 0 1997 2019
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 Signaling 445 0.413 0.885 0.13 0.040 None 1.000 4 0 2009 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.040 None 1.000 4 0 2000 2007
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.040 None 1.000 4 0 2002 2012
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.040 None 1.000 4 0 2011 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.030 None 1.000 3 0 1989 2001
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.030 None 1.000 3 0 2004 2018
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 490 0.403 0.769 1.9E-03 0.030 None 1.000 3 0 1999 2012
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.220 None 1.000 3 0 2006 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.030 None 1.000 3 0 2010 2017
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.030 None 1.000 3 0 2009 2012
Entrez Id: 84627
Gene Symbol: ZNF469
ZNF469
Q96JG9 zinc finger protein 469 101 0.584 0.769 0.72 0.030 None 1.000 3 0 1990 2004
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.030 None 1.000 3 0 1988 2004
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.030 None 1.000 3 0 1991 2014
Entrez Id: 617
Gene Symbol: BCS1L
BCS1L
Q9Y276 BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone 172 0.534 0.808 4.7E-13 0.030 None 1.000 3 0 1990 2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.020 None 1.000 2 0 2004 2014
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.020 None 1.000 2 0 2009 2012
Entrez Id: 6275
Gene Symbol: S100A4
S100A4
P26447 S100 calcium binding protein A4 Calcium-binding protein 308 0.448 0.769 6.2E-03 0.020 None 1.000 2 0 1998 1999
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.020 None 1.000 2 0 2018 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.020 None 1.000 2 0 2010 2012
Entrez Id: 2934
Gene Symbol: GSN
GSN
P06396 gelsolin Cellular structure 262 0.475 0.885 3.9E-11 0.020 None 1.000 2 0 2012 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.120 None 1.000 2 1 2009 2010
Entrez Id: 2980
Gene Symbol: GUCA2A
GUCA2A
Q02747 guanylate cyclase activator 2A 45 0.663 0.462 0.29 0.020 None 1.000 2 0 1998 2015
Entrez Id: 406933
Gene Symbol: MIR141
MIR141
microRNA 141 179 0.497 0.808 0.020 None 1.000 2 0 2017 2018