Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 351
Gene Symbol: APP
APP 		P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.600 None 0.980 202 11 1993 2020
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1 		Q92743 HtrA serine peptidase 1 Enzyme 164 0.532 0.692 4.9E-04 0.410 strong 1.000 2 1 2014 2015
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3 		Q9UM47 notch receptor 3 418 0.435 0.808 0.41 0.400 strong 1.000 12 1 2007 2019
Entrez Id: 5819
Gene Symbol: NECTIN2
NECTIN2 		Q92692 nectin cell adhesion molecule 2 106 0.575 0.769 0.97 0.400 None 1.000 2 1 2018 2019
Entrez Id: 1191
Gene Symbol: CLU
CLU 		P10909 clusterin 412 0.426 0.885 7.8E-05 0.380 None 1.000 9 1 2011 2019
Entrez Id: 8301
Gene Symbol: PICALM
PICALM 		Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 79 0.592 0.538 1.00 0.360 None 1.000 7 0 2011 2018
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C 		Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 225 0.510 0.846 1.00 0.340 None 1.000 4 2 2014 2018
Entrez Id: 6653
Gene Symbol: SORL1
SORL1 		Q92673 sortilin related receptor 1 Transporter 103 0.582 0.692 7.7E-11 0.330 None 1.000 4 1 2013 2018
Entrez Id: 274
Gene Symbol: BIN1
BIN1 		O00499 bridging integrator 1 163 0.550 0.692 0.78 0.320 None 1.000 3 0 2014 2018
Entrez Id: 79152
Gene Symbol: FA2H
FA2H 		Q7L5A8 fatty acid 2-hydroxylase Enzyme 131 0.573 0.654 0.15 0.310 strong 1.000 2 0 2013 2019
Entrez Id: 23621
Gene Symbol: BACE1
BACE1 		P56817 beta-secretase 1 Enzyme 120 0.559 0.769 0.88 0.300 None 0.963 27 0 2006 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.300 None 1.000 23 0 2007 2019
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1 		P02462 collagen type IV alpha 1 chain 277 0.484 0.731 1.00 0.300 strong 1.000 1 0 2007 2007
Entrez Id: 1378
Gene Symbol: CR1
CR1 		P17927 complement C3b/C4b receptor 1 (Knops blood group) 129 0.533 0.808 1.6E-35 0.300 None 1.000 1 2 2018 2018
Entrez Id: 338811
Gene Symbol: TAFA2
TAFA2 		Q8N3H0 TAFA chemokine like family member 2 15 0.780 0.192 0.34 0.300 None 1.000 1 0 2018 2018
Entrez Id: 8893
Gene Symbol: EIF2B5
EIF2B5 		Q13144 eukaryotic translation initiation factor 2B subunit epsilon 84 0.615 0.769 6.4E-02 0.300 None 1.000 1 0 1977 1977
Entrez Id: 102
Gene Symbol: ADAM10
ADAM10 		O14672 ADAM metallopeptidase domain 10 224 0.489 0.846 1.00 0.240 None 1.000 5 0 2009 2019
Entrez Id: 84687
Gene Symbol: PPP1R9B
PPP1R9B 		Q96SB3 protein phosphatase 1 regulatory subunit 9B 42 0.678 0.423 1.00 0.210 None 1.000 2 0 2013 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.200 None 0.989 181 5 2006 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.200 None 1.000 23 0 2012 2019
Entrez Id: 1756
Gene Symbol: DMD
DMD 		P11532 dystrophin 484 0.423 0.923 1.00 0.200 None 0.857 14 0 1994 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.200 None 0.917 12 1 2013 2020
Entrez Id: 6323
Gene Symbol: SCN1A
SCN1A 		P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 287 0.477 0.808 1.00 0.200 None 1.000 10 0 2001 2019
Entrez Id: 10096
Gene Symbol: ACTR3
ACTR3 		P61158 actin related protein 3 Cellular structure 31 0.686 0.385 1.00 0.200 None 1.000 1 0 2013 2013
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.190 None 1.000 9 0 2011 2020