Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.370 None 1.000 8 0 2005 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.350 None 1.000 6 1 2002 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.330 None 1.000 4 0 2002 2018
Entrez Id: 84680
Gene Symbol: ACCS
ACCS
Q96QU6 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Enzyme 161 0.522 0.731 9.0E-07 0.090 None 1.000 9 1 2006 2019
Entrez Id: 23659
Gene Symbol: PLA2G15
PLA2G15
Q8NCC3 phospholipase A2 group XV Enzyme 170 0.520 0.769 0.38 0.090 None 1.000 9 0 2006 2019
Entrez Id: 55902
Gene Symbol: ACSS2
ACSS2
Q9NR19 acyl-CoA synthetase short chain family member 2 Enzyme 188 0.506 0.808 1.1E-13 0.090 None 1.000 9 0 2006 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.080 None 0.875 8 0 2003 2018
Entrez Id: 4068
Gene Symbol: SH2D1A
SH2D1A
O60880 SH2 domain containing 1A 160 0.525 0.731 0.39 0.060 None 1.000 6 0 2009 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.060 None 1.000 6 0 2004 2018
Entrez Id: 325
Gene Symbol: APCS
APCS
P02743 amyloid P component, serum 141 0.531 0.808 3.2E-02 0.060 None 1.000 6 0 2009 2019
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
Q13093 phospholipase A2 group VII Enzyme 136 0.537 0.769 5.3E-22 0.040 None 0.750 4 0 2004 2018
Entrez Id: 1557
Gene Symbol: CYP2C19
CYP2C19
P33261 cytochrome P450 family 2 subfamily C member 19 274 0.467 0.846 6.5E-20 0.040 None 1.000 4 0 2011 2015
Entrez Id: 940
Gene Symbol: CD28
CD28
P10747 CD28 molecule 364 0.436 0.885 0.36 0.040 None 1.000 4 0 2000 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.030 None 0.667 3 0 2011 2019
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
Q9H244 purinergic receptor P2Y12 G-protein coupled receptor 153 0.533 0.731 1.7E-03 0.030 None 1.000 3 0 2013 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.030 None 1.000 3 0 2003 2018
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
P05154 serpin family A member 5 Enzyme modulator 185 0.507 0.808 6.2E-09 0.030 None 1.000 3 0 2017 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.030 None 1.000 3 0 2015 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.030 None 1.000 3 0 2003 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.030 None 1.000 3 0 2007 2018
Entrez Id: 929
Gene Symbol: CD14
CD14
P08571 CD14 molecule 551 0.392 0.885 4.9E-05 0.030 None 1.000 3 0 2005 2015
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.030 None 1.000 3 0 2008 2017
Entrez Id: 790
Gene Symbol: CAD
CAD
P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 249 0.482 0.846 1.00 0.030 None 1.000 3 0 2012 2019
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
Q9NSA1 fibroblast growth factor 21 Signaling 236 0.485 0.769 2.9E-02 0.020 None 1.000 2 0 2018 2019
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.020 None 1.000 2 0 2017 2019