Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 657
Gene Symbol: BMPR1A
BMPR1A
P36894 bone morphogenetic protein receptor type 1A Kinase 203 0.522 0.731 0.90 1.000 definitive 0.978 46 49 1993 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 1.000 definitive 0.980 102 88 1997 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.400 None 1.000 15 0 1997 2019
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.010 None 1.000 1 0 1997 1997
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 Kinase 372 0.435 0.808 0.99 0.030 None 1.000 3 0 1999 2013
Entrez Id: 4090
Gene Symbol: SMAD5
SMAD5
Q99717 SMAD family member 5 Transcription factor 55 0.633 0.615 1.00 0.010 None 1.000 1 0 1999 1999
Entrez Id: 1630
Gene Symbol: DCC
DCC
P43146 DCC netrin 1 receptor 279 0.471 0.808 0.99 0.010 None 1.000 1 0 1999 1999
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.010 None 1.000 1 0 2000 2000
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
Q99626 caudal type homeobox 2 Transcription factor 278 0.458 0.769 0.53 0.010 None 1.000 1 0 2001 2001
Entrez Id: 659
Gene Symbol: BMPR2
BMPR2
Q13873 bone morphogenetic protein receptor type 2 Kinase 146 0.538 0.654 1.00 0.010 None 1.000 1 0 2004 2004
Entrez Id: 2022
Gene Symbol: ENG
ENG
P17813 endoglin 371 0.446 0.846 1.00 0.630 limited 1.000 7 0 2005 2016
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
P37023 activin A receptor like type 1 Kinase 224 0.493 0.769 9.7E-04 0.030 None 1.000 3 0 2006 2013
Entrez Id: 780903
Gene Symbol: HHT3
HHT3
Osler-Rendu-Weber syndrome 3 1 1.000 0.115 0.010 None 1.000 1 0 2006 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.030 None 1.000 3 0 2007 2016
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase Enzyme 156 0.521 0.769 1.3E-18 0.020 None 1.000 2 0 2007 2008
Entrez Id: 4629
Gene Symbol: MYH11
MYH11
P35749 myosin heavy chain 11 161 0.528 0.731 0.77 0.010 None 1.000 1 0 2008 2008
Entrez Id: 650
Gene Symbol: BMP2
BMP2
P12643 bone morphogenetic protein 2 Signaling 428 0.432 0.846 0.99 0.010 None 1.000 1 0 2008 2008
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 224 0.483 0.808 1.0E-08 0.010 None 1.000 1 0 2009 2009
Entrez Id: 1994
Gene Symbol: ELAVL1
ELAVL1
Q15717 ELAV like RNA binding protein 1 103 0.560 0.731 0.99 0.010 None 1.000 1 0 2009 2009
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 310 0.449 0.846 9.0E-04 0.020 None 1.000 2 0 2010 2013
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.020 None 0.500 2 1 2011 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.030 None 1.000 3 0 2012 2018
Entrez Id: 4153
Gene Symbol: MBL2
MBL2
P11226 mannose binding lectin 2 Receptor 563 0.390 0.846 2.7E-03 0.020 None 1.000 2 0 2012 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.020 None 1.000 2 0 2012 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.010 None 1.000 1 0 2012 2012