Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 1.000 16 0 2011 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.040 None 0.750 4 0 2018 2019
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.040 None 1.000 4 0 2011 2017
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7
O14733 mitogen-activated protein kinase kinase 7 Kinase 408 0.419 0.808 1.00 0.020 None 1.000 2 0 2018 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.020 None 1.000 2 0 2018 2018
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.020 None 1.000 2 0 2018 2018
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.020 None 1.000 2 0 2005 2015
Entrez Id: 6723
Gene Symbol: SRM
SRM
P19623 spermidine synthase Enzyme 37 0.666 0.577 0.23 0.010 None 1.000 1 0 2016 2016
Entrez Id: 7204
Gene Symbol: TRIO
TRIO
O75962 trio Rho guanine nucleotide exchange factor Kinase 143 0.556 0.731 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
Q12882 dihydropyrimidine dehydrogenase Enzyme 249 0.493 0.846 3.4E-22 0.010 None 1.000 1 0 2015 2015
Entrez Id: 7364
Gene Symbol: UGT2B7
UGT2B7
P16662 UDP glucuronosyltransferase family 2 member B7 53 0.647 0.500 1.2E-13 0.010 None 1.000 1 0 2015 2015
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
O43490 prominin 1 Transporter 477 0.410 0.846 1.9E-22 0.010 None 1.000 1 0 2019 2019
Entrez Id: 8877
Gene Symbol: SPHK1
SPHK1
Q9NYA1 sphingosine kinase 1 Kinase 236 0.480 0.808 3.0E-07 0.010 None 1.000 1 0 2015 2015
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 420 0.419 0.885 2.1E-32 0.010 None 1.000 1 0 2015 2015
Entrez Id: 5340
Gene Symbol: PLG
PLG
P00747 plasminogen Enzyme 586 0.389 0.923 1.0E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 Nuclear receptor 528 0.400 0.923 4.5E-08 0.010 None 1.000 1 0 2019 2019
Entrez Id: 216
Gene Symbol: ALDH1A1
ALDH1A1
P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 270 0.460 0.846 0.95 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.010 None 1.000 1 0 2015 2015
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.010 None 1.000 1 0 2014 2014
Entrez Id: 3791
Gene Symbol: KDR
KDR
P35968 kinase insert domain receptor Kinase 623 0.378 0.885 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4486
Gene Symbol: MST1R
MST1R
Q04912 macrophage stimulating 1 receptor Kinase 133 0.542 0.808 7.9E-37 0.010 None 1.000 1 0 2011 2011