Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 1.000 limited 0.982 1885 25 1992 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 1.000 strong 0.975 315 6 1972 2020
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.900 strong 0.948 135 29 1996 2020
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.800 None 0.963 27 28 2003 2019
Entrez Id: 4477
Gene Symbol: MSMB
MSMB 		P08118 microseminoprotein beta Signaling 195 0.498 0.846 1.6E-02 0.700 None 0.984 63 2 1993 2020
Entrez Id: 8405
Gene Symbol: SPOP
SPOP 		O43791 speckle type BTB/POZ protein 72 0.597 0.500 1.00 0.700 None 0.957 46 4 2012 2020
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 508 0.401 0.808 0.15 0.700 limited 0.903 31 3 1997 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.700 None 0.960 25 4 1994 2019
Entrez Id: 4601
Gene Symbol: MXI1
MXI1 		P50539 MAX interactor 1, dimerization protein Transcription factor 128 0.547 0.615 1.1E-03 0.660 None 1.000 6 2 1995 2001
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1368 0.303 0.885 1.00 0.600 None 0.979 95 1 1998 2020
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13 		Q92826 homeobox B13 90 0.573 0.462 3.7E-08 0.600 None 0.982 57 2 2004 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.600 None 0.952 42 0 1998 2020
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4 		P22455 fibroblast growth factor receptor 4 Kinase 220 0.490 0.769 7.2E-13 0.600 None 0.929 14 2 2004 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.600 None 1.000 13 0 2005 2018
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.600 None 1.000 11 0 2006 2018
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		Q99801 NK3 homeobox 1 Transcription factor 22 0.722 0.269 4.7E-04 0.550 None 1.000 11 2 1999 2018
Entrez Id: 6715
Gene Symbol: SRD5A1
SRD5A1 		P18405 steroid 5 alpha-reductase 1 Enzyme 48 0.631 0.538 1.2E-05 0.550 None 1.000 8 2 2006 2017
Entrez Id: 354
Gene Symbol: KLK3
KLK3 		P07288 kallikrein related peptidase 3 Enzyme 358 0.443 0.885 4.4E-06 0.500 None 0.958 1867 15 1989 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.500 None 0.952 310 9 1991 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.500 None 0.984 127 1 2005 2020
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.500 None 0.928 111 6 1995 2020
Entrez Id: 6041
Gene Symbol: RNASEL
RNASEL 		Q05823 ribonuclease L Kinase 85 0.579 0.692 2.0E-10 0.500 None 0.871 62 6 2002 2019
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2 		P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.500 None 1.000 39 5 2001 2019
Entrez Id: 100750225
Gene Symbol: PCAT1
PCAT1 		prostate cancer associated transcript 1 90 0.575 0.615 0.500 None 1.000 36 33 2005 2019
Entrez Id: 1316
Gene Symbol: KLF6
KLF6 		Q99612 Kruppel like factor 6 Nucleic acid binding 204 0.501 0.846 0.98 0.500 None 0.857 28 2 2001 2018