Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 260431
Gene Symbol: COPD
COPD
Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.010 None 1.000 1 0 2017 2017
Entrez Id: 57126
Gene Symbol: CD177
CD177
Q8N6Q3 CD177 molecule 75 0.595 0.654 0.010 None 1.000 1 0 2020 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.010 None 1.000 1 1 2006 2006
Entrez Id: 1585
Gene Symbol: CYP11B2
CYP11B2
P19099 cytochrome P450 family 11 subfamily B member 2 142 0.553 0.615 7.1E-19 0.010 None 1.000 1 0 2006 2006
Entrez Id: 23523
Gene Symbol: CABIN1
CABIN1
Q9Y6J0 calcineurin binding protein 1 Enzyme modulator 136 0.536 0.846 3.3E-17 0.010 None 1.000 1 0 2007 2007
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.010 None 1.000 1 0 2017 2017
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.010 None 1.000 1 0 2010 2010
Entrez Id: 410
Gene Symbol: ARSA
ARSA
P15289 arylsulfatase A Enzyme 376 0.448 0.923 1.1E-11 0.010 None 1.000 1 0 2018 2018
Entrez Id: 720
Gene Symbol: C4A
C4A
P0C0L4 P0C0L5 complement C4A (Rodgers blood group) Enzyme modulator 145 0.563 0.769 1.5E-11 0.010 None 1.000 1 0 1991 1991
Entrez Id: 7350
Gene Symbol: UCP1
UCP1
P25874 uncoupling protein 1 Transporter 124 0.545 0.769 1.7E-11 0.010 None 1.000 1 1 2009 2009
Entrez Id: 8639
Gene Symbol: AOC3
AOC3
Q16853 amine oxidase copper containing 3 106 0.561 0.769 6.3E-11 0.300 None 1.000 1 0 2012 2012
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.010 None < 0.001 1 1 2009 2009
Entrez Id: 1234
Gene Symbol: CCR5
CCR5
P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 508 0.398 0.885 4.3E-10 0.010 None 1.000 1 0 2007 2007
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
P80188 lipocalin 2 Enzyme 497 0.405 0.885 1.1E-09 0.300 None 1.000 1 0 2015 2015
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.010 None 1.000 1 0 2006 2006
Entrez Id: 9945
Gene Symbol: GFPT2
GFPT2
O94808 glutamine-fructose-6-phosphate transaminase 2 Enzyme 19 0.769 0.308 6.4E-09 0.010 None 1.000 1 0 2010 2010
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2
Q9NP85 NPHS2 stomatin family member, podocin Enzyme modulator 86 0.576 0.538 7.2E-09 0.020 None 1.000 2 0 2003 2014
Entrez Id: 1215
Gene Symbol: CMA1
CMA1
P23946 chymase 1 Enzyme 157 0.514 0.692 7.6E-09 0.010 None 1.000 1 0 2006 2006
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
P21917 dopamine receptor D4 G-protein coupled receptor 189 0.517 0.577 9.3E-09 0.010 None 1.000 1 0 2008 2008
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.010 None < 0.001 1 2 2005 2005
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.010 None 1.000 1 1 2006 2006
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.030 None 1.000 3 0 2010 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.010 None 1.000 1 2 2009 2009
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.010 None 1.000 1 0 2008 2008
Entrez Id: 4502
Gene Symbol: MT2A
MT2A
P02795 metallothionein 2A 117 0.553 0.808 1.2E-05 0.300 None 1.000 1 0 2016 2016