Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.010 None 1.000 1 0 2005 2005
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.010 None 1.000 1 0 2016 2016
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.050 None 1.000 5 0 2005 2019
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase Enzyme 794 0.359 0.962 1.6E-10 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2688
Gene Symbol: GH1
GH1
P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.080 None 1.000 8 0 2004 2017
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.010 None 1.000 1 0 2017 2017
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.010 None 1.000 1 0 2005 2005
Entrez Id: 3342
Gene Symbol: HTC2
HTC2
hypertrichosis 2 (generalized, congenital) 511 0.392 0.808 0.010 None 1.000 1 0 2003 2003
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 590 0.393 0.885 0.97 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6750
Gene Symbol: SST
SST
P61278 somatostatin Signaling 535 0.399 0.885 0.34 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A
P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 597 0.401 0.846 1.00 1.000 definitive 0.961 128 25 2000 2020
Entrez Id: 5617
Gene Symbol: PRL
PRL
P01236 prolactin Signaling 506 0.406 0.885 2.9E-07 0.020 None 1.000 2 0 2004 2005
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.010 None 1.000 1 0 1996 1996
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
P46527 cyclin dependent kinase inhibitor 1B 454 0.409 0.769 0.62 0.030 None 1.000 3 0 2011 2016
Entrez Id: 846
Gene Symbol: CASR
CASR
P41180 calcium sensing receptor G-protein coupled receptor 517 0.410 0.846 4.7E-02 0.060 None 0.833 6 0 2001 2019
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 519 0.410 0.885 1.7E-05 0.010 None 1.000 1 0 2006 2006
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 462 0.418 0.846 7.3E-09 0.020 None 1.000 2 0 2013 2019
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 536 0.420 0.885 0.68 0.050 None 1.000 5 1 2002 2018
Entrez Id: 353
Gene Symbol: APRT
APRT
P07741 adenine phosphoribosyltransferase 384 0.423 0.846 5.5E-13 0.040 None 1.000 4 0 2002 2005
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 427 0.426 0.885 0.99 0.010 None 1.000 1 0 2012 2012
Entrez Id: 1555
Gene Symbol: CYP2B6
CYP2B6
P20813 cytochrome P450 family 2 subfamily B member 6 388 0.428 0.846 1.9E-10 0.010 None 1.000 1 0 2016 2016
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
P25106 atypical chemokine receptor 3 G-protein coupled receptor 400 0.428 0.885 0.39 0.010 None 1.000 1 0 2012 2012