Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.030 None 1.000 3 0 2017 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.100 None 1.000 14 0 2009 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.060 None 1.000 6 0 2001 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.030 None 1.000 3 0 2006 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1410 0.299 0.962 3.7E-03 0.050 None 1.000 5 0 2017 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.010 None 1.000 1 0 2009 2009
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 1050 0.318 0.885 0.27 0.030 None 1.000 3 0 2005 2017
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 994 0.321 0.962 0.61 0.030 None 1.000 3 0 2010 2019
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		P60709 actin beta Cellular structure 957 0.325 0.923 0.99 0.040 None 1.000 4 0 2012 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 935 0.330 0.923 1.00 0.030 None 1.000 3 0 2018 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 839 0.333 0.923 1.1E-03 0.010 None 1.000 1 0 2010 2010
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 886 0.338 0.962 1.9E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 852 0.345 0.923 0.66 0.010 None 1.000 1 0 2017 2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1 		P10451 secreted phosphoprotein 1 715 0.353 0.885 2.1E-06 0.010 None 1.000 1 0 2014 2014
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 739 0.357 0.885 3.6E-03 0.020 None 1.000 2 0 2017 2018
Entrez Id: 847
Gene Symbol: CAT
CAT 		P04040 catalase Enzyme 638 0.359 0.962 1.6E-10 0.010 None 1.000 1 0 2018 2018
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 702 0.361 0.962 8.1E-04 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		O60603 toll like receptor 2 704 0.361 0.923 1.0E-06 0.010 None 1.000 1 0 2019 2019
Entrez Id: 183
Gene Symbol: AGT
AGT 		P01019 angiotensinogen Enzyme modulator 632 0.367 0.923 5.0E-08 0.020 None 1.000 2 1 2019 2019
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		P09429 high mobility group box 1 Nucleic acid binding 671 0.368 0.923 0.82 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A 		P04439 major histocompatibility complex, class I, A 583 0.370 0.846 1.3E-03 0.010 None 1.000 1 0 2019 2019