Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.050 None 1.000 5 4 2002 2009
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.100 None 0.966 29 3 1998 2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.080 None 1.000 8 3 2003 2019
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.070 None 1.000 7 3 1999 2019
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.060 None 0.833 6 3 2012 2019
Entrez Id: 4598
Gene Symbol: MVK
MVK
Q03426 mevalonate kinase Kinase 139 0.576 0.731 0.17 0.020 None 1.000 2 3 2005 2018
Entrez Id: 6529
Gene Symbol: SLC6A1
SLC6A1
P30531 solute carrier family 6 member 1 Transporter 106 0.592 0.538 1.00 0.010 None 1.000 1 3 2013 2013
Entrez Id: 6616
Gene Symbol: SNAP25
SNAP25
P60880 synaptosome associated protein 25 Transporter 283 0.489 0.808 0.99 0.100 None 0.917 12 2 2000 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.080 None 1.000 8 2 2002 2018
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.080 None 1.000 8 2 2006 2020
Entrez Id: 150
Gene Symbol: ADRA2A
ADRA2A
P08913 adrenoceptor alpha 2A G-protein coupled receptor 102 0.578 0.615 8.2E-04 0.050 None 0.600 5 2 2003 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.050 None 1.000 5 2 2010 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.040 None 1.000 4 2 2005 2016
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.040 None 1.000 4 2 2015 2018
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.040 None 1.000 4 2 2010 2019
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 289 0.473 0.846 0.51 0.030 None 1.000 3 2 2004 2017
Entrez Id: 10846
Gene Symbol: PDE10A
PDE10A
Q9Y233 phosphodiesterase 10A 97 0.619 0.615 1.00 0.020 None 1.000 2 2 2016 2019
Entrez Id: 4669
Gene Symbol: NAGLU
NAGLU
P54802 N-acetyl-alpha-glucosaminidase 152 0.546 0.769 1.4E-08 0.120 None 1.000 2 2 1992 1998
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 590 0.393 0.885 0.97 0.100 None 1.000 14 1 2004 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 11 1 2013 2020
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.100 None 1.000 10 1 2005 2016
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.070 None 1.000 7 1 2009 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.060 None 0.833 6 1 2000 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.160 None 1.000 6 1 2005 2017
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
P23975 solute carrier family 6 member 2 Transporter 238 0.490 0.846 8.2E-02 0.060 None 1.000 6 1 2004 2019