Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.100 None 1.000 12 18 2008 2013
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.100 None 1.000 10 27 2008 2013
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
P04035 3-hydroxy-3-methylglutaryl-CoA reductase 154 0.529 0.692 1.00 0.100 None 1.000 9 9 2008 2013
Entrez Id: 64241
Gene Symbol: ABCG8
ABCG8
Q9H221 ATP binding cassette subfamily G member 8 Transporter 116 0.573 0.538 2.4E-20 0.100 None 1.000 9 8 2009 2013
Entrez Id: 1952
Gene Symbol: CELSR2
CELSR2
Q9HCU4 cadherin EGF LAG seven-pass G-type receptor 2 G-protein coupled receptor 63 0.656 0.577 1.00 0.100 None 1.000 8 15 2008 2013
Entrez Id: 10452
Gene Symbol: TOMM40
TOMM40
O96008 translocase of outer mitochondrial membrane 40 Transporter 113 0.590 0.538 0.99 0.100 None 1.000 7 4 2008 2013
Entrez Id: 9415
Gene Symbol: FADS2
FADS2
O95864 fatty acid desaturase 2 140 0.575 0.692 1.00 0.100 None 1.000 6 7 2009 2013
Entrez Id: 10087
Gene Symbol: CERT1
CERT1
Q9Y5P4 ceramide transporter 1 Transporter 71 0.674 0.500 0.67 0.100 None 1.000 6 6 2009 2013
Entrez Id: 57794
Gene Symbol: SUGP1
SUGP1
Q8IWZ8 SURP and G-patch domain containing 1 Nucleic acid binding 72 0.623 0.615 1.00 0.100 None 1.000 6 3 2009 2013
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.100 None 1.000 5 24 2008 2012
Entrez Id: 3992
Gene Symbol: FADS1
FADS1
O60427 fatty acid desaturase 1 125 0.582 0.769 0.37 0.100 None 1.000 4 2 2009 2013
Entrez Id: 3250
Gene Symbol: HPR
HPR
P00739 haptoglobin-related protein Enzyme 94 0.578 0.615 5.5E-10 0.100 None 1.000 4 1 2010 2013
Entrez Id: 54957
Gene Symbol: TXNL4B
TXNL4B
Q9NX01 thioredoxin like 4B 19 0.931 0.077 4.4E-03 0.100 None 1.000 4 1 2010 2013
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 1.000 4 3 2012 2013
Entrez Id: 85440
Gene Symbol: DOCK7
DOCK7
Q96N67 dedicator of cytokinesis 7 Enzyme modulator 51 0.682 0.423 6.4E-06 0.100 None 1.000 3 6 2010 2013
Entrez Id: 8701
Gene Symbol: DNAH11
DNAH11
Q96DT5 dynein axonemal heavy chain 11 Enzyme 110 0.587 0.692 2.5E-58 0.100 None 1.000 3 1 2009 2013
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.100 None 1.000 3 3 2012 2012
Entrez Id: 341
Gene Symbol: APOC1
APOC1
P02654 apolipoprotein C1 95 0.581 0.577 0.22 0.100 None 1.000 3 4 2012 2012
Entrez Id: 350
Gene Symbol: APOH
APOH
P02749 apolipoprotein H 121 0.563 0.769 1.6E-15 0.100 None 1.000 3 3 2012 2013
Entrez Id: 8882
Gene Symbol: ZPR1
ZPR1
O75312 ZPR1 zinc finger 64 0.674 0.462 8.9E-09 0.100 None 1.000 3 2 2008 2013
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
HNF1A antisense RNA 1 70 0.621 0.538 0.100 None 1.000 3 2 2009 2013
Entrez Id: 401491
Gene Symbol: VLDLR-AS1
VLDLR-AS1
VLDLR antisense RNA 1 21 0.821 0.115 0.100 None 1.000 2 6 2012 2013
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 347 0.450 0.885 1.00 0.100 None 1.000 2 2 2012 2013
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.100 None 1.000 2 2 2012 2013
Entrez Id: 100533990
Gene Symbol: APOC4-APOC2
APOC4-APOC2
APOC4-APOC2 readthrough (NMD candidate) 23 0.821 0.308 0.100 None 1.000 2 1 2012 2012