Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.100 None 0.966 58 0 1983 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.963 27 0 1995 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 1.000 26 0 2017 2020
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.100 None 0.960 25 0 2005 2020
Entrez Id: 1084
Gene Symbol: CEACAM3
CEACAM3
P40198 CEA cell adhesion molecule 3 204 0.494 0.731 1.1E-09 0.100 None 0.957 23 0 1983 2019
Entrez Id: 1087
Gene Symbol: CEACAM7
CEACAM7
Q14002 CEA cell adhesion molecule 7 202 0.494 0.769 1.3E-07 0.100 None 0.957 23 0 1983 2019
Entrez Id: 5670
Gene Symbol: PSG2
PSG2
P11465 pregnancy specific beta-1-glycoprotein 2 210 0.492 0.731 1.4E-30 0.100 None 0.957 23 0 1983 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.100 None 1.000 18 0 1997 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.100 None 0.933 15 0 1995 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.100 None 1.000 14 0 1995 2018
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.100 None 1.000 14 0 2017 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.100 None 1.000 14 0 1998 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.100 None 1.000 12 0 2001 2019
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.100 None 1.000 10 0 1995 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.100 None 1.000 10 0 1996 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.090 None 1.000 9 0 1994 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.090 None 1.000 9 0 2012 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.090 None 1.000 9 0 2003 2019
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.090 None 1.000 9 0 2000 2019
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
Q12882 dihydropyrimidine dehydrogenase Enzyme 249 0.493 0.846 3.4E-22 0.090 None 1.000 9 0 1999 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.090 None 0.889 9 0 2002 2019
Entrez Id: 4830
Gene Symbol: NME1
NME1
P15531 NME/NM23 nucleoside diphosphate kinase 1 Kinase 329 0.443 0.808 3.2E-03 0.090 None 0.889 9 0 1993 2007
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.090 None 1.000 9 0 2012 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.090 None 1.000 9 0 2006 2019
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.090 None 1.000 9 0 2003 2017