Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.010 None 1.000 1 0 2012 2012
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.010 None < 0.001 1 0 2011 2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.020 None 1.000 2 0 2011 2012
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.010 None 1.000 1 0 2011 2011
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.010 None 1.000 1 0 2011 2011
Entrez Id: 6662
Gene Symbol: SOX9
SOX9
P48436 SRY-box transcription factor 9 466 0.419 0.846 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 1756
Gene Symbol: DMD
DMD
P11532 dystrophin 484 0.423 0.923 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
P02452 collagen type I alpha 1 chain 487 0.430 0.808 1.00 0.020 None 1.000 2 0 2015 2017
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 310 0.449 0.846 9.0E-04 0.050 None 1.000 5 0 2007 2019
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
P12272 parathyroid hormone like hormone 321 0.453 0.846 0.81 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
Q99626 caudal type homeobox 2 Transcription factor 278 0.458 0.769 0.53 0.010 None 1.000 1 0 2011 2011
Entrez Id: 2626
Gene Symbol: GATA4
GATA4
P43694 GATA binding protein 4 336 0.458 0.846 0.49 0.010 None 1.000 1 0 2011 2011
Entrez Id: 7439
Gene Symbol: BEST1
BEST1
O76090 bestrophin 1 Ion channel 292 0.465 0.885 1.8E-12 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3280
Gene Symbol: HES1
HES1
Q14469 hes family bHLH transcription factor 1 Transcription factor 243 0.468 0.885 0.71 0.010 None 1.000 1 0 2011 2011
Entrez Id: 50964
Gene Symbol: SOST
SOST
Q9BQB4 sclerostin 270 0.474 0.808 0.87 0.010 None 1.000 1 0 2017 2017
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1
Q8N474 secreted frizzled related protein 1 227 0.479 0.846 0.96 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5052
Gene Symbol: PRDX1
PRDX1
Q06830 peroxiredoxin 1 Enzyme 237 0.485 0.846 7.7E-10 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1278
Gene Symbol: COL1A2
COL1A2
P08123 collagen type I alpha 2 chain 271 0.486 0.846 1.00 0.020 None 1.000 2 0 2015 2018
Entrez Id: 250
Gene Symbol: ALPP
ALPP
P05187 alkaline phosphatase, placental Enzyme 209 0.487 0.808 1.8E-13 0.050 None 1.000 5 0 2007 2019
Entrez Id: 80150
Gene Symbol: ASRGL1
ASRGL1
Q7L266 asparaginase and isoaspartyl peptidase 1 Enzyme 205 0.494 0.808 2.8E-05 0.050 None 1.000 5 0 2007 2019
Entrez Id: 283120
Gene Symbol: H19
H19
H19 imprinted maternally expressed transcript 242 0.494 0.923 0.010 None 1.000 1 0 1998 1998
Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1
P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 247 0.498 0.808 5.0E-08 0.010 None 1.000 1 0 2012 2012