Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1361 0.288 0.962 0.47 0.010 None 1.000 1 0 2020 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.100 None 1.000 10 0 2001 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.010 None 1.000 1 0 2017 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.020 None 1.000 2 0 2017 2019
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 1089 0.317 0.962 0.64 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1105 0.319 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1087 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1077 0.322 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1034 0.324 0.923 4.3E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		P60709 actin beta Cellular structure 957 0.325 0.923 0.99 0.020 None 1.000 2 0 2017 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2 		P04141 colony stimulating factor 2 Signaling 951 0.330 0.962 0.83 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 816 0.337 0.885 3.2E-10 0.020 None 1.000 2 1 2011 2019
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 886 0.338 0.962 1.9E-03 0.030 None 1.000 3 0 2006 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 839 0.344 0.885 1.3E-05 0.010 None 1.000 1 1 2010 2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 852 0.345 0.923 0.66 0.070 None 1.000 7 3 2009 2017
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 762 0.351 0.846 0.99 0.010 None 1.000 1 0 2009 2009
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 757 0.352 0.885 1.7E-05 0.040 None 1.000 4 0 2016 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 698 0.358 0.885 2.9E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		P35228 nitric oxide synthase 2 572 0.364 0.923 4.0E-15 0.020 None 1.000 2 0 1998 2006