Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.370 None 0.750 4 0 2000 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.300 None 1.000 1 0 2008 2008
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.330 None 1.000 4 0 1998 2014
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 179 0.287 0.962 3.7E-02 0.310 None 1.000 1 0 2001 2001
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 167 0.266 0.923 2.4E-05 0.310 None 1.000 2 0 2013 2013
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		P14416 dopamine receptor D2 G-protein coupled receptor 133 0.436 0.846 0.75 0.500 None 0.800 5 1 1996 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 119 0.345 0.923 0.66 0.400 None 1.000 5 0 2002 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 113 0.324 0.962 1.00 0.340 None 1.000 4 0 2008 2018
Entrez Id: 5020
Gene Symbol: OXT
OXT 		P01178 oxytocin/neurophysin I prepropeptide Signaling 110 0.615 0.423 0.71 0.300 None 1.000 1 0 2010 2010
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 110 0.358 0.885 2.9E-02 0.300 None 1.000 1 0 2014 2014
Entrez Id: 4852
Gene Symbol: NPY
NPY 		P01303 neuropeptide Y Signaling 109 0.447 0.846 0.14 0.380 None 1.000 5 0 1987 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 109 0.311 0.962 0.98 0.330 None 1.000 2 0 2004 2016
Entrez Id: 1392
Gene Symbol: CRH
CRH 		P06850 corticotropin releasing hormone Signaling 107 0.439 0.808 0.72 0.400 None 1.000 5 0 2001 2019
Entrez Id: 5173
Gene Symbol: PDYN
PDYN 		P01213 prodynorphin Signaling 102 0.535 0.577 1.7E-04 0.330 None 1.000 5 0 2000 2012
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A 		P29274 adenosine A2a receptor G-protein coupled receptor 101 0.526 0.769 0.60 0.310 None 1.000 1 0 2006 2006
Entrez Id: 5617
Gene Symbol: PRL
PRL 		P01236 prolactin Signaling 97 0.406 0.885 2.9E-07 0.340 None 1.000 1 0 2009 2020
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 93 0.522 0.846 0.20 0.400 None 1.000 5 0 1995 2019
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		P10635 cytochrome P450 family 2 subfamily D member 6 93 0.437 0.885 1.1E-25 0.320 None 1.000 1 0 2004 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		Q96EB6 sirtuin 1 Epigenetic regulator 89 0.378 0.885 8.7E-02 0.310 None 1.000 2 0 2010 2011
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 89 0.327 0.923 0.98 0.310 None 1.000 1 0 2013 2013
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 82 0.400 0.923 1.1E-06 0.400 None 0.800 5 0 1982 2019
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		P09038 fibroblast growth factor 2 Signaling 81 0.383 0.923 1.8E-02 0.330 None 1.000 3 0 2009 2018
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		P20366 tachykinin precursor 1 77 0.424 0.923 0.75 0.370 None 1.000 5 0 1987 2013
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4 		P31645 solute carrier family 6 member 4 Transporter 75 0.429 0.808 0.25 0.600 None 0.800 6 0 1996 2019
Entrez Id: 5428
Gene Symbol: POLG
POLG 		P54098 DNA polymerase gamma, catalytic subunit Enzyme 68 0.457 0.846 2.1E-09 0.520 None 1.000 1 0 2004 2017