Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.370 None 0.750 4 0 2000 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 167 0.266 0.923 2.4E-05 0.310 None 1.000 2 0 2013 2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 179 0.287 0.962 3.7E-02 0.310 None 1.000 1 0 2001 2001
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 109 0.311 0.962 0.98 0.330 None 1.000 2 0 2004 2016
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.300 None 1.000 1 0 2008 2008
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 113 0.324 0.962 1.00 0.340 None 1.000 4 0 2008 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 89 0.327 0.923 0.98 0.310 None 1.000 1 0 2013 2013
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.330 None 1.000 4 0 1998 2014
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 119 0.345 0.923 0.66 0.400 None 1.000 5 0 2002 2020
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 63 0.351 0.846 0.99 0.320 None 1.000 1 0 2006 2017
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 110 0.358 0.885 2.9E-02 0.300 None 1.000 1 0 2014 2014
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		Q96EB6 sirtuin 1 Epigenetic regulator 89 0.378 0.885 8.7E-02 0.310 None 1.000 2 0 2010 2011
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		P09038 fibroblast growth factor 2 Signaling 81 0.383 0.923 1.8E-02 0.330 None 1.000 3 0 2009 2018
Entrez Id: 6285
Gene Symbol: S100B
S100B 		P04271 S100 calcium binding protein B Calcium-binding protein 44 0.383 0.923 4.4E-02 0.330 None 0.500 2 0 2007 2019
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		O60760 hematopoietic prostaglandin D synthase 11 0.388 0.923 1.8E-06 0.310 None 1.000 1 0 2015 2015
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1 		P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 43 0.393 0.885 0.97 0.600 None 0.800 6 0 2002 2018
Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4 		P34932 heat shock protein family A (Hsp70) member 4 7 0.394 0.923 1.00 0.310 None 1.000 1 0 2010 2010
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		P19838 nuclear factor kappa B subunit 1 Transcription factor 33 0.396 0.923 1.00 0.300 None 1.000 1 0 2012 2012
Entrez Id: 6750
Gene Symbol: SST
SST 		P61278 somatostatin Signaling 56 0.399 0.885 0.34 0.310 None 1.000 1 0 1987 2015
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 82 0.400 0.923 1.1E-06 0.400 None 0.800 5 0 1982 2019
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1 		P26358 DNA methyltransferase 1 Epigenetic regulator 57 0.406 0.885 1.00 0.310 None 1.000 1 0 2011 2011
Entrez Id: 5617
Gene Symbol: PRL
PRL 		P01236 prolactin Signaling 97 0.406 0.885 2.9E-07 0.340 None 1.000 1 0 2009 2020
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 59 0.410 0.923 6.8E-08 0.320 None 1.000 2 0 2006 2018
Entrez Id: 3320
Gene Symbol: HSP90AA1
HSP90AA1 		P07900 heat shock protein 90 alpha family class A member 1 Chaperone 15 0.411 0.923 0.86 0.300 None 1.000 1 0 2011 2011
Entrez Id: 3240
Gene Symbol: HP
HP 		P00738 haptoglobin Enzyme 62 0.412 0.885 1.7E-05 0.340 None 1.000 2 0 1981 2018