Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.400 None 0.867 15 0 1997 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 0.909 11 0 1995 2018
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.100 None 1.000 10 2 1998 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.380 None 1.000 8 0 2003 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.080 None 1.000 8 2 1999 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.070 None 0.857 7 1 2001 2007
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.060 None 1.000 6 2 2003 2007
Entrez Id: 2167
Gene Symbol: FABP4
FABP4
P15090 fatty acid binding protein 4 194 0.500 0.808 5.2E-05 0.050 None 1.000 5 0 2011 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.050 None 1.000 5 0 2009 2019
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.350 None 1.000 5 1 1998 2007
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.050 None 1.000 5 0 1998 2018
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
Q13093 phospholipase A2 group VII Enzyme 136 0.537 0.769 5.3E-22 0.040 None 1.000 4 1 2004 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.040 None 1.000 4 0 2006 2014
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.040 None 1.000 4 1 2007 2017
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 188 0.512 0.731 1.2E-23 0.040 None 1.000 4 1 2000 2012
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
Q9Y251 heparanase Enzyme 393 0.425 0.808 2.3E-14 0.030 None 1.000 3 0 2013 2015
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.330 None 0.667 3 1 2004 2012
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.030 None 1.000 3 2 2018 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.030 None 0.667 3 1 2004 2012
Entrez Id: 58191
Gene Symbol: CXCL16
CXCL16
Q9H2A7 C-X-C motif chemokine ligand 16 Signaling 178 0.502 0.769 3.5E-05 0.030 None 1.000 3 1 2010 2015
Entrez Id: 1803
Gene Symbol: DPP4
DPP4
P27487 dipeptidyl peptidase 4 Enzyme 451 0.420 0.808 7.3E-09 0.030 None 1.000 3 0 2017 2018
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.030 None 1.000 3 0 2008 2018
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.030 None 0.667 3 3 2006 2018
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
P30556 angiotensin II receptor type 1 G-protein coupled receptor 440 0.423 0.846 5.3E-04 0.030 None 1.000 3 1 2006 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.030 None 1.000 3 0 2003 2019