Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 41
Gene Symbol: ASIC1
ASIC1
P78348 acid sensing ion channel subunit 1 Ion channel 52 0.653 0.615 0.93 0.010 None 1.000 1 0 2017 2017
Entrez Id: 133
Gene Symbol: ADM
ADM
P35318 adrenomedullin Signaling 405 0.436 0.808 4.1E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 55107
Gene Symbol: ANO1
ANO1
Q5XXA6 anoctamin 1 Ion channel 175 0.516 0.769 0.87 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 1 2013 2013
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.010 None 1.000 1 0 2010 2010
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
P48061 C-X-C motif chemokine ligand 12 626 0.379 0.846 0.12 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.210 None 1.000 3 0 2017 2018
Entrez Id: 796
Gene Symbol: CALCA
CALCA
P01258 P06881 calcitonin related polypeptide alpha Signaling 467 0.416 0.923 1.6E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
P34972 cannabinoid receptor 2 G-protein coupled receptor 197 0.509 0.846 6.5E-06 0.020 None 1.000 2 0 2007 2017
Entrez Id: 1055
Gene Symbol: CECR
CECR
cat eye syndrome chromosome region 81 0.599 0.731 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.080 None 1.000 8 1 2005 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
P10635 cytochrome P450 family 2 subfamily D member 6 432 0.437 0.885 1.1E-25 0.020 None 1.000 2 0 2012 2018
Entrez Id: 1576
Gene Symbol: CYP3A4
CYP3A4
P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 291 0.462 0.885 5.8E-11 0.010 None 1.000 1 0 2014 2014
Entrez Id: 1577
Gene Symbol: CYP3A5
CYP3A5
P20815 cytochrome P450 family 3 subfamily A member 5 Enzyme 179 0.511 0.846 6.3E-17 0.020 None 1.000 2 0 2014 2016
Entrez Id: 168400
Gene Symbol: DDX53
DDX53
Q86TM3 DEAD-box helicase 53 117 0.568 0.846 0.66 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Q9Y6K1 DNA methyltransferase 3 alpha 350 0.445 0.846 7.4E-39 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.020 None 1.000 2 0 2007 2010
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 427 0.426 0.885 0.99 0.010 None 1.000 1 0 2011 2011
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
P24530 endothelin receptor type B G-protein coupled receptor 300 0.470 0.846 9.2E-03 0.020 None 1.000 2 0 2010 2011
Entrez Id: 2150
Gene Symbol: F2RL1
F2RL1
P55085 F2R like trypsin receptor 1 G-protein coupled receptor 256 0.480 0.769 1.5E-04 0.020 None 1.000 2 0 2010 2012
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
O00519 fatty acid amide hydrolase 177 0.545 0.692 4.4E-11 0.010 None 1.000 1 0 2018 2018
Entrez Id: 79792
Gene Symbol: GSDMD
GSDMD
P57764 gasdermin D 50 0.641 0.692 1.1E-13 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2643
Gene Symbol: GCH1
GCH1
P30793 GTP cyclohydrolase 1 Enzyme 254 0.511 0.846 0.90 0.010 None 1.000 1 0 2010 2010