Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1 		P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.100 None 1.000 10 1 2004 2020
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.080 None 1.000 8 1 2005 2020
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1 		Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 404 0.446 0.885 1.0E-16 0.050 None 1.000 5 0 2007 2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.020 None 1.000 2 0 2007 2010
Entrez Id: 1269
Gene Symbol: CNR2
CNR2 		P34972 cannabinoid receptor 2 G-protein coupled receptor 197 0.509 0.846 6.5E-06 0.020 None 1.000 2 0 2007 2017
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB 		P24530 endothelin receptor type B G-protein coupled receptor 300 0.470 0.846 9.2E-03 0.020 None 1.000 2 0 2010 2011
Entrez Id: 2150
Gene Symbol: F2RL1
F2RL1 		P55085 F2R like trypsin receptor 1 G-protein coupled receptor 256 0.480 0.769 1.5E-04 0.020 None 1.000 2 0 2010 2012
Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8 		P45983 mitogen-activated protein kinase 8 Kinase 520 0.397 0.885 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.010 None 1.000 1 0 2010 2010
Entrez Id: 2643
Gene Symbol: GCH1
GCH1 		P30793 GTP cyclohydrolase 1 Enzyme 254 0.511 0.846 0.90 0.010 None 1.000 1 0 2010 2010
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA 		P25101 endothelin receptor type A G-protein coupled receptor 427 0.426 0.885 0.99 0.010 None 1.000 1 0 2011 2011
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		P10635 cytochrome P450 family 2 subfamily D member 6 432 0.437 0.885 1.1E-25 0.020 None 1.000 2 0 2012 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 1 2013 2013
Entrez Id: 1577
Gene Symbol: CYP3A5
CYP3A5 		P20815 cytochrome P450 family 3 subfamily A member 5 Enzyme 179 0.511 0.846 6.3E-17 0.020 None 1.000 2 0 2014 2016
Entrez Id: 1576
Gene Symbol: CYP3A4
CYP3A4 		P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 291 0.462 0.885 5.8E-11 0.010 None 1.000 1 0 2014 2014
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2 		O15393 transmembrane serine protease 2 Enzyme 69 0.615 0.500 2.4E-10 0.010 None 1.000 1 0 2015 2015
Entrez Id: 4803
Gene Symbol: NGF
NGF 		P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.040 None 0.750 4 0 2017 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4 		P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.210 None 1.000 3 0 2017 2018
Entrez Id: 4986
Gene Symbol: OPRK1
OPRK1 		P41145 opioid receptor kappa 1 G-protein coupled receptor 156 0.555 0.615 4.1E-05 0.020 None 1.000 2 0 2017 2018
Entrez Id: 10280
Gene Symbol: SIGMAR1
SIGMAR1 		Q99720 sigma non-opioid intracellular receptor 1 190 0.544 0.808 0.17 0.020 None 1.000 2 0 2017 2017
Entrez Id: 3558
Gene Symbol: IL2
IL2 		P60568 interleukin 2 950 0.336 0.885 0.48 0.010 None 1.000 1 0 2017 2017
Entrez Id: 90865
Gene Symbol: IL33
IL33 		O95760 interleukin 33 487 0.409 0.885 8.3E-10 0.010 None 1.000 1 0 2017 2017
Entrez Id: 6616
Gene Symbol: SNAP25
SNAP25 		P60880 synaptosome associated protein 25 Transporter 283 0.489 0.808 0.99 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.010 None 1.000 1 0 2017 2017