Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.010 None 1.000 1 0 2015 2015
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.010 None 1.000 1 0 2007 2007
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.030 None 1.000 3 0 1996 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.010 None 1.000 1 1 2014 2014
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 Kinase 816 0.362 0.885 1.00 0.030 None 1.000 3 0 2015 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.010 None 1.000 1 0 2003 2003
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.010 None 1.000 1 0 2004 2004
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.200 None 1.000 2 0 2017 2017
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2353
Gene Symbol: FOS
FOS
P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 528 0.411 0.885 0.26 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.020 None 1.000 2 0 2010 2019
Entrez Id: 25
Gene Symbol: ABL1
ABL1
P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 395 0.432 0.923 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 3725
Gene Symbol: JUN
JUN
P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 344 0.442 0.885 6.0E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6777
Gene Symbol: STAT5B
STAT5B
P51692 signal transducer and activator of transcription 5B Nucleic acid binding 357 0.442 0.808 1.00 0.010 None 1.000 1 0 2009 2009
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8
P28908 TNF receptor superfamily member 8 301 0.444 0.808 0.86 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6776
Gene Symbol: STAT5A
STAT5A
P42229 signal transducer and activator of transcription 5A Nucleic acid binding 318 0.445 0.808 1.00 0.010 None 1.000 1 0 2009 2009
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
P36888 fms related receptor tyrosine kinase 3 Kinase 270 0.462 0.654 0.61 0.020 None 1.000 2 0 2011 2017
Entrez Id: 2354
Gene Symbol: FOSB
FOSB
P53539 FosB proto-oncogene, AP-1 transcription factor subunit Transcription factor 278 0.463 0.846 0.98 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
P17275 JunB proto-oncogene, AP-1 transcription factor subunit Transcription factor 264 0.467 0.769 0.86 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3727
Gene Symbol: JUND
JUND
P17535 JunD proto-oncogene, AP-1 transcription factor subunit Transcription factor 242 0.475 0.808 0.70 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3562
Gene Symbol: IL3
IL3
P08700 interleukin 3 211 0.489 0.731 2.6E-09 0.010 None 1.000 1 0 1991 1991
Entrez Id: 6664
Gene Symbol: SOX11
SOX11
P35716 SRY-box transcription factor 11 Transcription factor 246 0.494 0.808 0.86 0.010 None 1.000 1 0 2009 2009
Entrez Id: 3159
Gene Symbol: HMGA1
HMGA1
P17096 high mobility group AT-hook 1 Nucleic acid binding 206 0.494 0.769 0.83 0.200 None 0 0
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
P29597 tyrosine kinase 2 Kinase 172 0.505 0.769 4.5E-08 0.010 None 1.000 1 0 2004 2004
Entrez Id: 406953
Gene Symbol: MIR18A
MIR18A
microRNA 18a 154 0.520 0.846 0.010 None 1.000 1 0 2018 2018