Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.460 None 1.000 32 6 2003 2019
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		O43502 RAD51 paralog C 162 0.533 0.692 6.2E-14 0.500 None 1.000 26 14 2010 2020
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D 		O75771 RAD51 paralog D 36 0.674 0.385 1.1E-09 0.420 None 1.000 19 7 2010 2018
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1 		Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 194 0.507 0.731 6.2E-17 0.410 None 1.000 14 9 2005 2019
Entrez Id: 580
Gene Symbol: BARD1
BARD1 		Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.400 None 1.000 13 6 2004 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.050 None 1.000 5 0 2000 2016
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.150 None 1.000 5 1 2000 2015
Entrez Id: 5395
Gene Symbol: PMS2
PMS2 		P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.040 None 1.000 4 0 2000 2019
Entrez Id: 4683
Gene Symbol: NBN
NBN 		O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.400 None 1.000 3 2 2003 2014
Entrez Id: 4361
Gene Symbol: MRE11
MRE11 		P49959 MRE11 homolog, double strand break repair nuclease 171 0.527 0.808 1.3E-12 0.400 None 1.000 3 1 2003 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.330 None 1.000 3 0 2000 2013
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		Q92878 RAD50 double strand break repair protein 110 0.556 0.808 3.4E-27 0.300 None 1.000 2 0 2003 2011
Entrez Id: 4360
Gene Symbol: MRC1
MRC1 		P22897 mannose receptor C-type 1 431 0.413 0.846 0.94 0.020 None 1.000 2 0 2007 2013
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1 		P07477 serine protease 1 Enzyme 117 0.563 0.692 4.1E-11 0.020 None 1.000 2 0 2004 2014
Entrez Id: 85348
Gene Symbol: KRT88P
KRT88P 		keratin 88 pseudogene 24 0.705 0.385 0.020 None 1.000 2 0 1999 2015
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.020 None 1.000 2 1 2010 2011
Entrez Id: 5888
Gene Symbol: RAD51
RAD51 		Q06609 RAD51 recombinase 363 0.447 0.846 2.7E-02 0.300 None 1.000 2 0 2000 2014
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.020 None 1.000 2 0 2000 2001
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.010 None 1.000 1 0 1996 1996
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3 		Q9UM47 notch receptor 3 418 0.435 0.808 0.41 0.010 None 1.000 1 0 2014 2014
Entrez Id: 8045
Gene Symbol: RASSF7
RASSF7 		Q02833 Ras association domain family member 7 56 0.621 0.538 2.3E-11 0.010 None 1.000 1 0 1996 1996
Entrez Id: 4771
Gene Symbol: NF2
NF2 		P35240 neurofibromin 2 312 0.468 0.885 1.00 0.010 None 1.000 1 0 1995 1995
Entrez Id: 4437
Gene Symbol: MSH3
MSH3 		P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.010 None 1.000 1 0 2000 2000
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 508 0.401 0.808 0.15 0.010 None 1.000 1 0 2018 2018
Entrez Id: 51478
Gene Symbol: HSD17B7
HSD17B7 		P56937 hydroxysteroid 17-beta dehydrogenase 7 81 0.582 0.500 6.6E-06 0.010 None 1.000 1 0 1993 1993