Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 846
Gene Symbol: CASR
CASR 		P41180 calcium sensing receptor G-protein coupled receptor 517 0.410 0.846 4.7E-02 0.100 None 1.000 14 10 2003 2017
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.100 None 0.976 83 7 1994 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.972 247 6 1991 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.100 None 0.936 78 6 1992 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.100 None 0.985 135 5 1983 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.980 102 5 1989 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 0.955 22 5 1999 2015
Entrez Id: 1591
Gene Symbol: CYP24A1
CYP24A1 		Q07973 cytochrome P450 family 24 subfamily A member 1 Enzyme 171 0.518 0.692 3.2E-23 0.040 None 1.000 4 5 2001 2011
Entrez Id: 3551
Gene Symbol: IKBKB
IKBKB 		O14920 inhibitor of nuclear factor kappa B kinase subunit beta Kinase 191 0.506 0.846 0.99 0.010 None 1.000 1 5 2010 2010
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.400 None 0.978 90 4 2003 2019
Entrez Id: 5395
Gene Symbol: PMS2
PMS2 		P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.100 None 1.000 14 4 2011 2019
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 156 0.521 0.769 1.3E-18 0.400 None 1.000 11 4 2005 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.100 None 1.000 10 4 2013 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.050 None 1.000 5 4 2012 2019
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B 		P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 224 0.502 0.846 9.9E-07 0.010 None 1.000 1 4 2018 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.967 90 3 1995 2019
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.100 None 0.957 47 3 1994 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 1.000 30 3 1990 2020
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.100 None 0.957 23 3 1998 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.100 None 1.000 17 3 2010 2019
Entrez Id: 4092
Gene Symbol: SMAD7
SMAD7 		O15105 SMAD family member 7 Transcription factor 269 0.470 0.769 0.55 0.060 None 1.000 6 3 2009 2016
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1 		P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.040 None 0.750 4 3 2009 2013
Entrez Id: 54106
Gene Symbol: TLR9
TLR9 		Q9NR96 toll like receptor 9 457 0.411 0.885 9.8E-06 0.030 None 1.000 3 3 2007 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.100 None 0.985 65 2 1989 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.400 None 1.000 44 2 1998 2019