Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.700 None 0.937 142 7 1996 2020
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
P10914 interferon regulatory factor 1 Transcription factor 257 0.468 0.769 0.99 0.650 limited 1.000 6 3 1998 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.600 None 0.960 374 5 1988 2020
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.600 strong 0.957 47 0 1996 2019
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase Enzyme 156 0.521 0.769 1.3E-18 0.540 None 1.000 5 4 2004 2015
Entrez Id: 843
Gene Symbol: CASP10
CASP10
Q92851 caspase 10 Enzyme 166 0.528 0.692 4.6E-12 0.510 None 1.000 1 1 2002 2002
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.400 None 0.992 121 0 2003 2020
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.400 None 0.983 60 1 1991 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.400 None 0.967 30 6 1987 2019
Entrez Id: 7031
Gene Symbol: TFF1
TFF1
P04155 trefoil factor 1 Signaling 147 0.529 0.769 8.9E-04 0.400 None 1.000 28 4 2000 2019
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.400 None 1.000 21 3 1992 2019
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.400 None 1.000 20 0 1998 2019
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.400 None 1.000 14 1 2003 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 Kinase 372 0.435 0.808 0.99 0.390 None 1.000 9 1 1998 2019
Entrez Id: 1316
Gene Symbol: KLF6
KLF6
Q99612 Kruppel like factor 6 Nucleic acid binding 204 0.501 0.846 0.98 0.360 None 1.000 6 0 2005 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.360 None 1.000 6 0 2003 2018
Entrez Id: 51366
Gene Symbol: UBR5
UBR5
O95071 ubiquitin protein ligase E3 component n-recognin 5 73 0.597 0.654 1.00 0.320 None 1.000 2 0 2006 2016
Entrez Id: 5426
Gene Symbol: POLE
POLE
Q07864 DNA polymerase epsilon, catalytic subunit 151 0.526 0.731 8.0E-27 0.310 None 1.000 1 0 2013 2013
Entrez Id: 545
Gene Symbol: ATR
ATR
Q13535 ATR serine/threonine kinase Kinase 321 0.456 0.923 3.5E-09 0.310 None 1.000 1 0 1999 1999
Entrez Id: 84260
Gene Symbol: TCHP
TCHP
Q9BT92 trichoplein keratin filament binding 90 0.570 0.692 1.8E-16 0.310 None 1.000 1 1 2019 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.300 None 0.960 50 1 2005 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.300 None 0.955 22 1 2003 2019
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
P09486 secreted protein acidic and cysteine rich Signaling 344 0.445 0.846 0.89 0.300 None 1.000 13 0 2002 2019
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
Q9Y2T1 axin 2 169 0.507 0.692 0.57 0.300 None 0 0
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
O15392 baculoviral IAP repeat containing 5 Enzyme modulator 199 0.495 0.731 5.6E-02 0.220 None 1.000 3 0 2003 2019