Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 396 0.401 0.808 0.15 0.700 None 0.937 142 5 1996 2020
Entrez Id: 3659
Gene Symbol: IRF1
IRF1 		P10914 interferon regulatory factor 1 Transcription factor 230 0.468 0.769 0.99 0.650 limited 1.000 5 1 1998 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.600 None 0.960 372 4 1988 2020
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 345 0.380 0.808 1.00 0.600 strong 0.957 46 0 1996 2019
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 130 0.521 0.769 1.3E-18 0.540 None 1.000 4 2 2004 2015
Entrez Id: 843
Gene Symbol: CASP10
CASP10 		Q92851 caspase 10 Enzyme 84 0.528 0.692 4.6E-12 0.510 None 1.000 1 0 2002 2002
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.400 None 0.992 121 0 2003 2020
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 501 0.380 0.846 0.97 0.400 None 0.983 60 1 1991 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.400 None 0.967 29 2 1987 2019
Entrez Id: 7031
Gene Symbol: TFF1
TFF1 		P04155 trefoil factor 1 Signaling 137 0.529 0.769 8.9E-04 0.400 None 1.000 28 3 2000 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 517 0.373 0.962 1.00 0.400 None 1.000 21 0 1992 2019
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 563 0.374 0.885 5.6E-47 0.400 None 1.000 20 0 1998 2019
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3 		P21860 erb-b2 receptor tyrosine kinase 3 Kinase 263 0.448 0.808 1.7E-15 0.400 None 1.000 14 1 2003 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 303 0.435 0.808 0.99 0.390 None 1.000 9 0 1998 2019
Entrez Id: 1316
Gene Symbol: KLF6
KLF6 		Q99612 Kruppel like factor 6 Nucleic acid binding 192 0.501 0.846 0.98 0.360 None 1.000 6 0 2005 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.360 None 1.000 6 0 2003 2018
Entrez Id: 51366
Gene Symbol: UBR5
UBR5 		O95071 ubiquitin protein ligase E3 component n-recognin 5 65 0.597 0.654 1.00 0.320 None 1.000 2 0 2006 2016
Entrez Id: 5426
Gene Symbol: POLE
POLE 		Q07864 DNA polymerase epsilon, catalytic subunit 93 0.526 0.731 8.0E-27 0.310 None 1.000 1 0 2013 2013
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 223 0.456 0.923 3.5E-09 0.310 None 1.000 1 0 1999 1999
Entrez Id: 84260
Gene Symbol: TCHP
TCHP 		Q9BT92 trichoplein keratin filament binding 86 0.570 0.692 1.8E-16 0.310 None 1.000 1 0 2019 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.300 None 0.960 49 1 2005 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 826 0.333 0.923 0.84 0.300 None 0.955 21 1 2003 2019
Entrez Id: 6678
Gene Symbol: SPARC
SPARC 		P09486 secreted protein acidic and cysteine rich Signaling 291 0.445 0.846 0.89 0.300 None 1.000 12 0 2002 2019
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5 		O15392 baculoviral IAP repeat containing 5 Enzyme modulator 137 0.495 0.731 5.6E-02 0.220 None 1.000 2 0 2003 2019
Entrez Id: 8000
Gene Symbol: PSCA
PSCA 		O43653 prostate stem cell antigen 103 0.555 0.615 0.17 0.200 None 1.000 42 4 2008 2019