Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.100 None 1.000 29 0 2006 2020
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 470 0.362 0.885 1.00 0.100 None 1.000 29 0 2016 2020
Entrez Id: 340348
Gene Symbol: TSPAN33
TSPAN33 		Q86UF1 tetraspanin 33 69 0.606 0.731 7.0E-05 0.100 None 1.000 26 0 2002 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.100 None 1.000 25 0 2007 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.400 None 1.000 23 0 2002 2020
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 722 0.351 0.923 0.10 0.100 None 1.000 19 0 2016 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1604 0.276 0.962 0.13 0.400 None 1.000 17 0 2014 2019
Entrez Id: 100128998
Gene Symbol: C20orf181
C20orf181 		chromosome 20 open reading frame 181 245 0.479 0.885 0.100 None 1.000 17 0 2010 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 852 0.345 0.923 0.66 0.100 None 1.000 16 0 2002 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.100 None 0.933 15 0 1999 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1030 0.321 0.962 4.6E-09 0.100 None 1.000 13 0 2015 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 953 0.327 0.923 0.98 0.100 None 1.000 11 0 2014 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.100 None 1.000 11 0 2017 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1087 0.320 0.885 1.4E-06 0.100 None 1.000 10 0 2017 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1105 0.319 0.885 1.00 0.100 None 1.000 10 0 2017 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1077 0.322 0.885 1.00 0.100 None 1.000 10 0 2017 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.100 None 1.000 10 0 2017 2019
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		P14136 glial fibrillary acidic protein 411 0.421 0.885 1.5E-06 0.100 None 1.000 10 0 2010 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 739 0.357 0.885 3.6E-03 0.100 None 1.000 10 0 2017 2020
Entrez Id: 1641
Gene Symbol: DCX
DCX 		O43602 doublecortin 152 0.511 0.769 0.30 0.090 None 1.000 9 0 2004 2019
Entrez Id: 2056
Gene Symbol: EPO
EPO 		P01588 erythropoietin 560 0.381 0.885 1.1E-02 0.080 None 1.000 8 0 2017 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.380 None 1.000 8 0 2009 2020
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12 		P48061 C-X-C motif chemokine ligand 12 593 0.379 0.846 0.12 0.080 None 1.000 8 0 2017 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 702 0.361 0.962 8.1E-04 0.070 None 1.000 7 0 2018 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.070 None 1.000 7 0 1999 2019