Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.300 None 1.000 1 0 1984 1984
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.010 None 1.000 1 0 1992 1992
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.220 None 1.000 3 0 1993 2007
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.020 None 1.000 2 0 1993 2015
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.050 None 1.000 5 0 1995 2000
Entrez Id: 7799
Gene Symbol: PRDM2
PRDM2
Q13029 PR/SET domain 2 115 0.545 0.769 1.00 0.010 None 1.000 1 0 1996 1996
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
P49789 fragile histidine triad diadenosine triphosphatase 337 0.444 0.846 5.7E-03 0.010 None 1.000 1 0 1997 1997
Entrez Id: 6608
Gene Symbol: SMO
SMO
Q99835 smoothened, frizzled class receptor G-protein coupled receptor 215 0.489 0.731 4.3E-07 0.300 None 1.000 1 0 1998 1998
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.300 None 1.000 1 0 1998 1998
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.050 None 1.000 5 0 1999 2019
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.020 None 1.000 2 0 1999 2007
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.020 None 1.000 2 0 1999 2007
Entrez Id: 2706
Gene Symbol: GJB2
GJB2
P29033 gap junction protein beta 2 Cell-cell junction 392 0.441 0.846 6.6E-16 0.010 None 1.000 1 0 1999 1999
Entrez Id: 2697
Gene Symbol: GJA1
GJA1
P17302 gap junction protein alpha 1 Cell-cell junction 662 0.393 0.885 0.16 0.010 None 1.000 1 0 1999 1999
Entrez Id: 4673
Gene Symbol: NAP1L1
NAP1L1
P55209 nucleosome assembly protein 1 like 1 Enzyme modulator 53 0.647 0.692 1.00 0.010 None 1.000 1 0 2000 2000
Entrez Id: 10133
Gene Symbol: OPTN
OPTN
Q96CV9 optineurin 136 0.548 0.808 5.9E-18 0.010 None 1.000 1 0 2000 2000
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
O14786 neuropilin 1 246 0.476 0.808 0.99 0.010 None 1.000 1 0 2000 2000
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 2001 2001
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.010 None 1.000 1 0 2001 2001
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.320 None 1.000 3 0 2003 2010
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.310 None 1.000 3 0 2004 2015
Entrez Id: 7052
Gene Symbol: TGM2
TGM2
P21980 transglutaminase 2 Enzyme 315 0.445 0.808 6.8E-18 0.300 None 1.000 1 0 2005 2005
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
Q15672 twist family bHLH transcription factor 1 Transcription factor 559 0.397 0.846 0.34 0.010 None 1.000 1 0 2005 2005
Entrez Id: 64101
Gene Symbol: LRRC4
LRRC4
Q9HBW1 leucine rich repeat containing 4 57 0.617 0.577 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.300 None 1.000 1 0 2005 2005