Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.310 1.000 2 0 2014 2017
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 293 0.438 0.759 1.1E-07 0.310 1.000 2 0 2007 2010
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen nucleic acid binding 372 0.417 0.759 0.98 0.310 1.000 2 0 1999 2011
Entrez Id: 7052
Gene Symbol: TGM2
TGM2
P21980 transglutaminase 2 transferase 171 0.499 0.690 7.0E-18 0.310 1.000 2 0 2006 2011
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box 2 transcription factor 251 0.459 0.759 0.73 0.310 1.000 2 0 2012 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.300 2 0 2004 2007
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.300 2 0 2011 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 hydrolase; nucleic acid binding 325 0.432 0.828 8.2E-02 0.300 1 0 2012 2012
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 564 0.373 0.931 0.49 0.300 1 0 1984 1984
Entrez Id: 3689
Gene Symbol: ITGB2
ITGB2
P05107 integrin subunit beta 2 cell adhesion molecule; extracellular matrix protein; receptor 189 0.496 0.828 7.8E-15 0.300 1 0 2017 2017
Entrez Id: 6285
Gene Symbol: S100B
S100B
P04271 S100 calcium binding protein B calcium-binding protein; signaling molecule 301 0.443 0.862 4.7E-02 0.300 1 0 2017 2017
Entrez Id: 10788
Gene Symbol: IQGAP2
IQGAP2
Q13576 IQ motif containing GTPase activating protein 2 enzyme modulator 30 0.713 0.207 2.1E-25 0.300 1 0 2017 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
P46937 Yes associated protein 1 149 0.514 0.655 1.00 0.300 1 0 2017 2017
Entrez Id: 8826
Gene Symbol: IQGAP1
IQGAP1
P46940 IQ motif containing GTPase activating protein 1 enzyme modulator 65 0.600 0.586 1.00 0.300 1 0 2017 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.300 1 0 2011 2011
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.300 1 0 2012 2012
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 481 0.391 0.862 1.0E-06 0.300 1 0 2006 2006
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 324 0.443 0.828 9.0E-11 0.300 1 0 2005 2005
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 386 0.435 0.759 1.00 0.300 1 0 1998 1998
Entrez Id: 6608
Gene Symbol: SMO
SMO
Q99835 smoothened, frizzled class receptor enzyme modulator; receptor; signaling molecule 141 0.520 0.690 8.0E-07 0.300 1 0 1998 1998
Entrez Id: 5970
Gene Symbol: RELA
RELA
Q04206 RELA proto-oncogene, NF-kB subunit nucleic acid binding; transcription factor 245 0.456 0.828 1.00 0.300 1 0 2011 2011
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 kinase; receptor; transferase 361 0.437 0.793 0.15 0.300 1 0 2017 2017
Entrez Id: 24147
Gene Symbol: FJX1
FJX1
Q86VR8 four jointed box 1 19 0.735 0.310 0.95 0.300 1 0 2017 2017
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase 274 0.448 0.724 3.5E-06 0.300 1 0 2013 2013
Entrez Id: 441478
Gene Symbol: NRARP
NRARP
Q7Z6K4 NOTCH regulated ankyrin repeat protein 7 0.834 0.069 0.22 0.300 1 0 2011 2011