Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
O43490 prominin 1 Transporter 477 0.410 0.846 1.9E-22 0.010 None 1.000 1 0 2009 2009
Entrez Id: 5970
Gene Symbol: RELA
RELA
Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 483 0.406 0.885 1.00 0.300 None 1.000 1 0 2011 2011
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.300 None 1.000 1 0 2017 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.200 None 1.000 1 0 2007 2007
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.300 None 1.000 1 0 2011 2011
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3689
Gene Symbol: ITGB2
ITGB2
P05107 integrin subunit beta 2 Receptor 340 0.444 0.923 5.1E-15 0.300 None 1.000 1 0 2017 2017
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.300 None 1.000 1 0 2011 2011
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.300 None 1.000 1 0 2011 2011
Entrez Id: 1612
Gene Symbol: DAPK1
DAPK1
P53355 death associated protein kinase 1 Kinase 249 0.472 0.808 1.00 0.300 None 1.000 1 0 2007 2007
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.300 None 1.000 1 0 2012 2012
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.300 None 1.000 1 0 2017 2017
Entrez Id: 6608
Gene Symbol: SMO
SMO
Q99835 smoothened, frizzled class receptor G-protein coupled receptor 215 0.489 0.731 4.3E-07 0.300 None 1.000 1 0 1998 1998
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.300 None 1.000 1 0 2012 2012
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.300 None 1.000 2 0 2011 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
P46937 Yes associated protein 1 Enzyme modulator 374 0.432 0.808 1.00 0.300 None 1.000 1 0 2017 2017
Entrez Id: 10788
Gene Symbol: IQGAP2
IQGAP2
Q13576 IQ motif containing GTPase activating protein 2 Enzyme modulator 46 0.674 0.269 8.5E-27 0.300 None 1.000 1 0 2017 2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.300 None 1.000 1 0 2017 2017
Entrez Id: 8826
Gene Symbol: IQGAP1
IQGAP1
P46940 IQ motif containing GTPase activating protein 1 Enzyme modulator 109 0.560 0.692 1.00 0.300 None 1.000 1 0 2017 2017
Entrez Id: 113878
Gene Symbol: DTX2
DTX2
Q86UW9 deltex E3 ubiquitin ligase 2 Enzyme 10 0.792 0.077 2.9E-02 0.300 None 1.000 1 0 2010 2010
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.300 None 1.000 1 0 2011 2011
Entrez Id: 7052
Gene Symbol: TGM2
TGM2
P21980 transglutaminase 2 Enzyme 315 0.445 0.808 6.8E-18 0.300 None 1.000 1 0 2005 2005
Entrez Id: 6285
Gene Symbol: S100B
S100B
P04271 S100 calcium binding protein B Calcium-binding protein 599 0.383 0.923 4.4E-02 0.300 None 1.000 1 0 2017 2017