Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 8826
Gene Symbol: IQGAP1
IQGAP1
P46940 IQ motif containing GTPase activating protein 1 Enzyme modulator 109 0.560 0.692 1.00 0.300 None 1.000 1 0 2017 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.300 None 1.000 1 0 2012 2012
Entrez Id: 6608
Gene Symbol: SMO
SMO
Q99835 smoothened, frizzled class receptor G-protein coupled receptor 215 0.489 0.731 4.3E-07 0.300 None 1.000 1 0 1998 1998
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.300 None 1.000 1 0 2011 2011
Entrez Id: 1612
Gene Symbol: DAPK1
DAPK1
P53355 death associated protein kinase 1 Kinase 249 0.472 0.808 1.00 0.300 None 1.000 1 0 2007 2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.010 None 1.000 1 0 2017 2017
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.300 None 1.000 1 0 2012 2012
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.300 None 1.000 1 0 2017 2017
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.300 None 1.000 1 0 2011 2011
Entrez Id: 3689
Gene Symbol: ITGB2
ITGB2
P05107 integrin subunit beta 2 Receptor 340 0.444 0.923 5.1E-15 0.300 None 1.000 1 0 2017 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.320 None 1.000 3 0 1994 2011
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5970
Gene Symbol: RELA
RELA
Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 483 0.406 0.885 1.00 0.300 None 1.000 1 0 2011 2011
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.300 None 1.000 1 0 2017 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.200 None 1.000 1 0 2007 2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 1991 1991