Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 404 0.446 0.885 1.0E-16 0.400 None 1.000 15 0 2002 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.330 None 1.000 14 0 1995 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.320 None 1.000 8 0 1995 2017
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
P20366 tachykinin precursor 1 478 0.424 0.923 0.75 0.310 None 1.000 10 0 1996 2017
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.310 None 1.000 5 0 1996 2017
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
Q02156 protein kinase C epsilon Kinase 112 0.597 0.692 1.00 0.310 None 1.000 4 0 2001 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.310 None 1.000 3 0 1995 2007
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
Q13519 prepronociceptin Signaling 103 0.603 0.577 1.5E-02 0.310 None 1.000 3 0 2003 2015
Entrez Id: 5024
Gene Symbol: P2RX3
P2RX3
P56373 purinergic receptor P2X 3 Ion channel 125 0.565 0.769 1.0E-06 0.310 None 1.000 2 0 2009 2018
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.310 None 1.000 2 0 2008 2017
Entrez Id: 22953
Gene Symbol: P2RX2
P2RX2
Q9UBL9 purinergic receptor P2X 2 Ion channel 99 0.585 0.769 9.7E-13 0.310 None 1.000 2 0 2009 2018
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.310 None 1.000 2 0 2010 2014
Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8
P45983 mitogen-activated protein kinase 8 Kinase 520 0.397 0.885 1.00 0.310 None 1.000 2 0 2016 2017
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.310 None 1.000 2 0 2016 2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.310 None 1.000 2 0 2007 2017
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
P01042 kininogen 1 Enzyme modulator 279 0.481 0.885 3.2E-10 0.300 None 1.000 17 0 1988 2011
Entrez Id: 796
Gene Symbol: CALCA
CALCA
P01258 P06881 calcitonin related polypeptide alpha Signaling 467 0.416 0.923 1.6E-02 0.300 None 1.000 4 0 2003 2016
Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1
P46663 bradykinin receptor B1 G-protein coupled receptor 79 0.619 0.731 4.7E-03 0.300 None 1.000 3 0 2008 2010
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1
P54289 calcium voltage-gated channel auxiliary subunit alpha2delta 1 Ion channel 82 0.641 0.500 1.00 0.300 None 1.000 3 0 2001 2013
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.300 None 1.000 3 0 1995 2008
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
P30411 bradykinin receptor B2 G-protein coupled receptor 105 0.585 0.808 0.12 0.300 None 1.000 3 0 2008 2010
Entrez Id: 8989
Gene Symbol: TRPA1
TRPA1
O75762 transient receptor potential cation channel subfamily A member 1 Ion channel 160 0.546 0.846 7.2E-35 0.300 None 1.000 3 0 2008 2013
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.300 None 1.000 2 0 2007 2008
Entrez Id: 5582
Gene Symbol: PRKCG
PRKCG
P05129 protein kinase C gamma Kinase 90 0.617 0.500 1.00 0.300 None 1.000 2 0 2009 2016
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.300 None 1.000 2 0 2003 2016