Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
Q9NSA1 fibroblast growth factor 21 Signaling 236 0.485 0.769 2.9E-02 0.100 None 0.882 17 0 2012 2019
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
Q99988 growth differentiation factor 15 Signaling 389 0.429 0.808 3.0E-07 0.100 None 0.900 10 0 2015 2020
Entrez Id: 2395
Gene Symbol: FXN
FXN
Q16595 frataxin Enzyme 220 0.510 0.654 0.34 0.090 None 1.000 9 0 1997 2020
Entrez Id: 9997
Gene Symbol: SCO2
SCO2
O43819 synthesis of cytochrome C oxidase 2 Enzyme 294 0.479 0.846 7.5E-07 0.350 strong 1.000 6 0 1999 2016
Entrez Id: 6834
Gene Symbol: SURF1
SURF1
Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 150 0.578 0.654 1.6E-13 0.350 strong 1.000 6 0 1998 2016
Entrez Id: 4694
Gene Symbol: NDUFA1
NDUFA1
O15239 NADH:ubiquinone oxidoreductase subunit A1 74 0.636 0.423 0.55 0.330 strong 1.000 5 0 1988 2017
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 316 0.474 0.846 2.4E-04 0.340 None 1.000 5 0 2012 2019
Entrez Id: 57132
Gene Symbol: CHMP1B
CHMP1B
Q7LBR1 charged multivesicular body protein 1B Transporter 24 0.736 0.462 0.73 0.050 None 1.000 5 0 2010 2014
Entrez Id: 1890
Gene Symbol: TYMP
TYMP
P19971 thymidine phosphorylase Enzyme 246 0.495 0.769 1.2E-04 0.050 None 1.000 5 0 1999 2018
Entrez Id: 6341
Gene Symbol: SCO1
SCO1
O75880 synthesis of cytochrome C oxidase 1 Enzyme 71 0.638 0.769 2.2E-04 0.520 strong 1.000 4 0 2007 2019
Entrez Id: 4724
Gene Symbol: NDUFS4
NDUFS4
O43181 NADH:ubiquinone oxidoreductase subunit S4 137 0.587 0.808 3.1E-04 0.330 strong 1.000 4 0 2016 2019
Entrez Id: 1371
Gene Symbol: CPOX
CPOX
P36551 coproporphyrinogen oxidase Enzyme 246 0.488 0.846 0.17 0.040 None 1.000 4 0 1997 2014
Entrez Id: 1351
Gene Symbol: COX8A
COX8A
P10176 cytochrome c oxidase subunit 8A Enzyme 526 0.400 0.846 0.12 0.040 None 1.000 4 0 1997 2014
Entrez Id: 57176
Gene Symbol: VARS2
VARS2
Q5ST30 valyl-tRNA synthetase 2, mitochondrial 37 0.666 0.577 5.8E-17 0.040 None 1.000 4 0 2014 2019
Entrez Id: 7035
Gene Symbol: TFPI
TFPI
P10646 tissue factor pathway inhibitor Enzyme modulator 230 0.486 0.808 0.25 0.040 None 1.000 4 0 2012 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha Transcription factor 350 0.453 0.885 1.00 0.040 None 1.000 4 0 2009 2019
Entrez Id: 54968
Gene Symbol: TMEM70
TMEM70
Q9BUB7 transmembrane protein 70 83 0.636 0.654 2.9E-02 0.330 strong 1.000 4 0 2010 2016
Entrez Id: 9377
Gene Symbol: COX5A
COX5A
P20674 cytochrome c oxidase subunit 5A Enzyme 171 0.515 0.846 0.49 0.040 None 1.000 4 0 1997 2014
Entrez Id: 7084
Gene Symbol: TK2
TK2
O00142 thymidine kinase 2 Kinase 143 0.585 0.615 3.9E-07 0.030 None 1.000 3 0 2008 2016
Entrez Id: 6652
Gene Symbol: SORD
SORD
Q00796 sorbitol dehydrogenase Enzyme 113 0.552 0.769 4.5E-08 0.030 None 1.000 3 0 2012 2017
Entrez Id: 56945
Gene Symbol: MRPS22
MRPS22
P82650 mitochondrial ribosomal protein S22 78 0.638 0.500 1.5E-05 0.030 None 1.000 3 0 2007 2018
Entrez Id: 54802
Gene Symbol: TRIT1
TRIT1
Q9H3H1 tRNA isopentenyltransferase 1 Enzyme 73 0.621 0.692 4.1E-11 0.030 None 1.000 3 0 2017 2019
Entrez Id: 79133
Gene Symbol: NDUFAF5
NDUFAF5
Q5TEU4 NADH:ubiquinone oxidoreductase complex assembly factor 5 70 0.674 0.462 3.1E-10 0.320 strong 1.000 3 0 2008 2016
Entrez Id: 80224
Gene Symbol: NUBPL
NUBPL
Q8TB37 nucleotide binding protein like 77 0.670 0.423 1.1E-05 0.510 strong 1.000 3 0 2010 2016
Entrez Id: 1757
Gene Symbol: SARDH
SARDH
Q9UL12 sarcosine dehydrogenase Enzyme 166 0.523 0.846 5.3E-16 0.030 None 1.000 3 0 2012 2017