Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
P55081 microfibril associated protein 1 Extracellular structure 357 0.431 0.846 0.80 0.020 None 1.000 2 0 2007 2013
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
Q12778 forkhead box O1 380 0.433 0.846 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
Q9UM47 notch receptor 3 418 0.435 0.808 0.41 0.010 None 1.000 1 0 2007 2007
Entrez Id: 6687
Gene Symbol: SPG7
SPG7
Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 419 0.436 0.885 2.0E-36 0.120 None 1.000 3 2 1999 2017
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
P04792 heat shock protein family B (small) member 1 395 0.436 0.808 2.8E-07 0.010 None 1.000 1 0 2012 2012
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 356 0.439 0.885 1.6E-72 0.020 None 1.000 2 0 2004 2017
Entrez Id: 1869
Gene Symbol: E2F1
E2F1
Q01094 E2F transcription factor 1 Nucleic acid binding 324 0.441 0.846 0.99 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
P33527 ATP binding cassette subfamily C member 1 Transporter 333 0.445 0.808 1.2E-03 0.010 None 1.000 1 0 2005 2005
Entrez Id: 7052
Gene Symbol: TGM2
TGM2
P21980 transglutaminase 2 Enzyme 315 0.445 0.808 6.8E-18 0.010 None 1.000 1 0 2017 2017
Entrez Id: 718
Gene Symbol: C3
C3
P01024 complement C3 Enzyme modulator 343 0.445 0.885 0.90 0.010 None 1.000 1 0 2015 2015
Entrez Id: 23476
Gene Symbol: BRD4
BRD4
O60885 bromodomain containing 4 Epigenetic regulator 335 0.446 0.885 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 410
Gene Symbol: ARSA
ARSA
P15289 arylsulfatase A Enzyme 376 0.448 0.923 1.1E-11 0.010 None 1.000 1 0 2006 2006
Entrez Id: 8988
Gene Symbol: HSPB3
HSPB3
Q12988 heat shock protein family B (small) member 3 327 0.448 0.769 6.1E-05 0.010 None 1.000 1 0 2012 2012
Entrez Id: 5080
Gene Symbol: PAX6
PAX6
P26367 paired box 6 340 0.450 0.769 1.00 0.010 None 1.000 1 0 2007 2007
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha Transcription factor 350 0.453 0.885 1.00 0.040 None 1.000 4 0 2009 2019
Entrez Id: 5428
Gene Symbol: POLG
POLG
P54098 DNA polymerase gamma, catalytic subunit Enzyme 462 0.457 0.846 2.1E-09 0.500 None 0.957 46 8 2003 2020
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
P05091 aldehyde dehydrogenase 2 family member Enzyme 337 0.457 0.885 3.4E-10 0.010 None 1.000 1 0 1996 1996
Entrez Id: 3316
Gene Symbol: HSPB2
HSPB2
Q16082 heat shock protein family B (small) member 2 290 0.457 0.769 3.3E-04 0.010 None 1.000 1 0 2012 2012
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
P07203 glutathione peroxidase 1 Enzyme 290 0.458 0.923 3.9E-05 0.010 None 1.000 1 0 2001 2001
Entrez Id: 3065
Gene Symbol: HDAC1
HDAC1
Q13547 histone deacetylase 1 Epigenetic regulator 277 0.460 0.846 0.61 0.010 None 1.000 1 0 2019 2019
Entrez Id: 9474
Gene Symbol: ATG5
ATG5
Q9H1Y0 autophagy related 5 Transporter 282 0.462 0.885 0.98 0.010 None 1.000 1 0 2015 2015
Entrez Id: 9927
Gene Symbol: MFN2
MFN2
O95140 mitofusin 2 Enzyme 334 0.471 0.846 0.99 0.030 None 1.000 3 0 2008 2019
Entrez Id: 6392
Gene Symbol: SDHD
SDHD
O14521 succinate dehydrogenase complex subunit D Transporter 348 0.472 0.885 0.34 0.300 strong 1.000 1 0 2016 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 316 0.474 0.846 2.4E-04 0.340 None 1.000 5 0 2012 2019