Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4763
Gene Symbol: NF1
NF1 		P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.400 None 1.000 43 0 1989 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.330 None 1.000 3 0 2006 2015
Entrez Id: 9644
Gene Symbol: SH3PXD2A
SH3PXD2A 		Q5TCZ1 SH3 and PX domains 2A 32 0.729 0.385 0.99 0.300 None 1.000 1 0 2016 2016
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1 		Q92743 HtrA serine peptidase 1 Enzyme 164 0.532 0.692 4.9E-04 0.300 None 1.000 1 0 2016 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.974 38 0 1993 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.100 None 1.000 27 0 1999 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.941 17 0 2002 2019
Entrez Id: 23512
Gene Symbol: SUZ12
SUZ12 		Q15022 SUZ12 polycomb repressive complex 2 subunit Nucleic acid binding 165 0.529 0.577 1.00 0.100 None 1.000 12 0 2014 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.090 None 1.000 9 0 1994 2018
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		O14733 mitogen-activated protein kinase kinase 7 Kinase 408 0.419 0.808 1.00 0.080 None 1.000 8 0 2013 2018
Entrez Id: 8726
Gene Symbol: EED
EED 		O75530 embryonic ectoderm development 123 0.588 0.615 1.00 0.070 None 1.000 7 0 2014 2019
Entrez Id: 6285
Gene Symbol: S100B
S100B 		P04271 S100 calcium binding protein B Calcium-binding protein 599 0.383 0.923 4.4E-02 0.070 None 1.000 7 0 2002 2019
Entrez Id: 6271
Gene Symbol: S100A1
S100A1 		P23297 S100 calcium binding protein A1 Calcium-binding protein 396 0.421 0.846 6.0E-03 0.070 None 1.000 7 0 2002 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.060 None 1.000 6 0 1999 2018
Entrez Id: 6598
Gene Symbol: SMARCB1
SMARCB1 		Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 448 0.434 0.846 1.00 0.060 None 1.000 6 0 2011 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.060 None 1.000 6 0 2008 2015
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.060 None 1.000 6 0 2014 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		H3 histone pseudogene 10 769 0.350 0.846 0.060 None 1.000 6 0 1999 2015
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.060 None 0.833 6 2 2008 2017
Entrez Id: 3084
Gene Symbol: NRG1
NRG1 		Q02297 neuregulin 1 Signaling 304 0.464 0.885 1.00 0.050 None 1.000 5 0 2004 2016
Entrez Id: 3082
Gene Symbol: HGF
HGF 		P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.050 None 1.000 5 0 2004 2018
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A 		P11388 DNA topoisomerase II alpha 200 0.497 0.731 0.99 0.050 None 1.000 5 0 2003 2017
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.050 None 1.000 5 0 2004 2019
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.050 None 1.000 5 0 2011 2019
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2 		P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.040 None 1.000 4 0 2013 2019