Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.030 None 0.667 3 0 1998 2011
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.020 None 1.000 2 0 2011 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1
P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.020 None 1.000 2 0 2004 2004
Entrez Id: 3342
Gene Symbol: HTC2
HTC2
hypertrichosis 2 (generalized, congenital) 511 0.392 0.808 0.020 None 1.000 2 0 2004 2005
Entrez Id: 412
Gene Symbol: STS
STS
P08842 steroid sulfatase Enzyme 382 0.431 0.846 0.81 0.010 None 1.000 1 0 1993 1993
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 405 0.445 0.923 0.30 0.010 None 1.000 1 0 1997 1997
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
P45452 matrix metallopeptidase 13 Enzyme 328 0.452 0.923 7.9E-18 0.010 None 1.000 1 0 2014 2014
Entrez Id: 51741
Gene Symbol: WWOX
WWOX
Q9NZC7 WW domain containing oxidoreductase Enzyme 356 0.453 0.808 1.2E-15 0.010 None 1.000 1 0 2014 2014
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
O15516 clock circadian regulator 309 0.463 0.885 1.00 0.030 None 1.000 3 0 2001 2013
Entrez Id: 5914
Gene Symbol: RARA
RARA
P10276 retinoic acid receptor alpha Nuclear receptor 274 0.470 0.846 0.96 0.030 None 1.000 3 0 2006 2017
Entrez Id: 5376
Gene Symbol: PMP22
PMP22
Q01453 peripheral myelin protein 22 Cellular structure 341 0.471 0.885 0.91 0.040 None 1.000 4 0 1993 2016
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
Q9BYX4 interferon induced with helicase C domain 1 319 0.471 0.808 7.0E-44 0.030 None 1.000 3 1 2015 2019
Entrez Id: 2332
Gene Symbol: FMR1
FMR1
Q06787 FMRP translational regulator 1 Nucleic acid binding 346 0.473 0.769 0.65 0.010 None 1.000 1 0 2015 2015
Entrez Id: 9759
Gene Symbol: HDAC4
HDAC4
P56524 histone deacetylase 4 Epigenetic regulator 256 0.484 0.885 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 6611
Gene Symbol: SMS
SMS
P52788 spermine synthase 263 0.491 0.846 0.97 0.130 None 0.667 3 1 2005 2018
Entrez Id: 5920
Gene Symbol: PLAAT4
PLAAT4
Q9UL19 phospholipase A and acyltransferase 4 190 0.500 0.808 1.2E-07 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 249 0.510 0.692 1.00 0.010 None 1.000 1 0 2014 2014
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1
P36956 sterol regulatory element binding transcription factor 1 159 0.518 0.808 1.5E-02 0.020 None 1.000 2 0 2003 2018
Entrez Id: 2314
Gene Symbol: FLII
FLII
Q13045 FLII actin remodeling protein 198 0.520 0.808 5.5E-12 0.300 None 1.000 3 0 1995 2005
Entrez Id: 23586
Gene Symbol: DDX58
DDX58
O95786 DExD/H-box helicase 58 144 0.526 0.808 1.8E-23 0.010 None 1.000 1 0 2015 2015
Entrez Id: 6281
Gene Symbol: S100A10
S100A10
P60903 S100 calcium binding protein A10 Calcium-binding protein 150 0.528 0.769 0.17 0.010 None 1.000 1 0 1996 1996
Entrez Id: 2572
Gene Symbol: GAD2
GAD2
Q05329 glutamate decarboxylase 2 Enzyme 173 0.529 0.731 0.75 0.020 None 1.000 2 0 1994 1997
Entrez Id: 2657
Gene Symbol: GDF1
GDF1
P27539 growth differentiation factor 1 Signaling 136 0.529 0.692 0.41 0.010 None 1.000 1 0 2017 2017
Entrez Id: 28954
Gene Symbol: REM1
REM1
O75628 RRAD and GEM like GTPase 1 177 0.531 0.885 5.3E-08 0.020 None 1.000 2 0 1996 2010
Entrez Id: 26121
Gene Symbol: PRPF31
PRPF31
Q8WWY3 pre-mRNA processing factor 31 Nucleic acid binding 150 0.531 0.731 0.98 0.010 None 1.000 1 0 2004 2004