Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.010 None 1.000 1 0 2006 2006
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.050 None 1.000 5 0 2009 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.020 None 1.000 2 0 2010 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.020 None 1.000 2 0 2015 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
P04141 colony stimulating factor 2 Signaling 1028 0.330 0.962 0.83 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.020 None 1.000 2 0 2009 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.010 None 1.000 1 0 2012 2012
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.010 None 1.000 1 0 2016 2016
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
P09919 colony stimulating factor 3 687 0.377 0.885 0.38 0.010 None 1.000 1 0 2007 2007
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
Q13753 laminin subunit gamma 2 Enzyme modulator 602 0.389 0.923 2.9E-12 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4153
Gene Symbol: MBL2
MBL2
P11226 mannose binding lectin 2 Receptor 563 0.390 0.846 2.7E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 490 0.403 0.769 1.9E-03 0.010 None 1.000 1 0 2016 2016
Entrez Id: 834
Gene Symbol: CASP1
CASP1
P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4615
Gene Symbol: MYD88
MYD88
Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 480 0.414 0.923 0.12 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
P13569 CF transmembrane conductance regulator Ion channel 476 0.424 0.885 2.2E-58 0.100 None 1.000 13 0 1996 2019
Entrez Id: 6279
Gene Symbol: S100A8
S100A8
P05109 S100 calcium binding protein A8 Calcium-binding protein 369 0.430 0.962 0.14 0.010 None 1.000 1 0 2013 2013
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
P09341 C-X-C motif chemokine ligand 1 Signaling 315 0.449 0.923 0.12 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
P45452 matrix metallopeptidase 13 Enzyme 328 0.452 0.923 7.9E-18 0.010 None 1.000 1 0 2015 2015
Entrez Id: 10673
Gene Symbol: TNFSF13B
TNFSF13B
Q9Y275 TNF superfamily member 13b 282 0.460 0.731 0.98 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3135
Gene Symbol: HLA-G
HLA-G
P17693 major histocompatibility complex, class I, G 279 0.461 0.769 1.4E-11 0.010 None 1.000 1 0 2016 2016
Entrez Id: 51164
Gene Symbol: DCTN4
DCTN4
Q9UJW0 dynactin subunit 4 253 0.472 0.846 0.73 0.320 None 1.000 2 0 2012 2016
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8
Q09428 ATP binding cassette subfamily C member 8 Transporter 317 0.474 0.846 8.0E-24 0.010 None 1.000 1 0 2013 2013
Entrez Id: 6850
Gene Symbol: SYK
SYK
P43405 spleen associated tyrosine kinase Kinase 229 0.475 0.808 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4321
Gene Symbol: MMP12
MMP12
P39900 matrix metallopeptidase 12 Enzyme 216 0.484 0.885 0.010 None 1.000 1 0 2015 2015