Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.060 None 1.000 6 0 2014 2019
Entrez Id: 4615
Gene Symbol: MYD88
MYD88
Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 480 0.414 0.923 0.12 0.050 None 1.000 5 0 2014 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.030 None 1.000 3 0 2014 2018
Entrez Id: 3459
Gene Symbol: IFNGR1
IFNGR1
P15260 interferon gamma receptor 1 Receptor 153 0.529 0.692 1.6E-02 0.030 None 1.000 3 0 1997 2014
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.020 None 1.000 2 0 2018 2019
Entrez Id: 3594
Gene Symbol: IL12RB1
IL12RB1
P42701 interleukin 12 receptor subunit beta 1 Signaling 118 0.555 0.731 9.4E-15 0.020 None 1.000 2 0 2018 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.020 None 1.000 2 0 2007 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.020 None 1.000 2 0 2017 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.010 None 1.000 1 0 2011 2011
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.010 None 1.000 1 0 2018 2018
Entrez Id: 59067
Gene Symbol: IL21
IL21
Q9HBE4 interleukin 21 321 0.441 0.769 0.63 0.010 None 1.000 1 0 2018 2018
Entrez Id: 100187716
Gene Symbol: MIR1224
MIR1224
microRNA 1224 36 0.666 0.385 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.010 None 1.000 1 0 2019 2019
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 Enzyme 480 0.404 0.923 3.7E-06 0.010 None 1.000 1 0 2007 2007
Entrez Id: 8517
Gene Symbol: IKBKG
IKBKG
Q9Y6K9 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Kinase 252 0.493 0.769 8.5E-02 0.010 None 1.000 1 0 2011 2011
Entrez Id: 8651
Gene Symbol: SOCS1
SOCS1
O15524 suppressor of cytokine signaling 1 Enzyme modulator 315 0.445 0.808 0.59 0.010 None 1.000 1 0 2018 2018
Entrez Id: 8772
Gene Symbol: FADD
FADD
Q13158 Fas associated via death domain 137 0.537 0.846 0.53 0.010 None 1.000 1 0 2007 2007
Entrez Id: 911
Gene Symbol: CD1C
CD1C
P29017 CD1c molecule 49 0.633 0.692 1.6E-08 0.010 None 1.000 1 0 2016 2016
Entrez Id: 55512
Gene Symbol: SMPD3
SMPD3
Q9NY59 sphingomyelin phosphodiesterase 3 50 0.659 0.615 0.59 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.010 None 1.000 1 0 2009 2009
Entrez Id: 50615
Gene Symbol: IL21R
IL21R
Q9HBE5 interleukin 21 receptor Receptor 110 0.550 0.731 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 10657
Gene Symbol: KHDRBS1
KHDRBS1
Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 289 0.457 0.846 0.99 0.010 None 1.000 1 0 2019 2019
Entrez Id: 115201
Gene Symbol: ATG4A
ATG4A
Q8WYN0 autophagy related 4A cysteine peptidase Enzyme 16 0.760 0.192 0.99 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1511
Gene Symbol: CTSG
CTSG
P08311 cathepsin G Enzyme 95 0.563 0.731 9.6E-06 0.010 None 1.000 1 0 2012 2012