Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.090 None 0.889 9 0 1994 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.040 None 0.500 4 0 1996 2007
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
Q8WXI7 mucin 16, cell surface associated 236 0.479 0.808 8.3E-112 0.040 None 1.000 4 0 2017 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.030 None 1.000 3 0 1997 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.020 None 1.000 2 0 1999 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.020 None 1.000 2 0 1998 2007
Entrez Id: 5266
Gene Symbol: PI3
PI3
P19957 peptidase inhibitor 3 Enzyme modulator 92 0.570 0.692 0.17 0.010 None 1.000 1 0 2014 2014
Entrez Id: 59067
Gene Symbol: IL21
IL21
Q9HBE4 interleukin 21 321 0.441 0.769 0.63 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5670
Gene Symbol: PSG2
PSG2
P11465 pregnancy specific beta-1-glycoprotein 2 210 0.492 0.731 1.4E-30 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5641
Gene Symbol: LGMN
LGMN
Q99538 legumain Enzyme 95 0.579 0.731 4.1E-04 0.010 None 1.000 1 0 2012 2012
Entrez Id: 55272
Gene Symbol: IMP3
IMP3
Q9NV31 IMP U3 small nucleolar ribonucleoprotein 3 Nucleic acid binding 97 0.566 0.462 1.5E-07 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.010 None 1.000 1 0 2000 2000
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.010 None 1.000 1 0 2002 2002
Entrez Id: 8678
Gene Symbol: BECN1
BECN1
Q14457 beclin 1 Enzyme modulator 373 0.432 0.846 0.94 0.010 None 1.000 1 0 2008 2008
Entrez Id: 83478
Gene Symbol: ARHGAP24
ARHGAP24
Q8N264 Rho GTPase activating protein 24 273 0.456 0.808 3.9E-10 0.010 None 1.000 1 0 2000 2000
Entrez Id: 8202
Gene Symbol: NCOA3
NCOA3
Q9Y6Q9 nuclear receptor coactivator 3 Kinase 142 0.522 0.654 0.54 0.010 None 1.000 1 0 2005 2005
Entrez Id: 80010
Gene Symbol: RMI1
RMI1
Q9H9A7 RecQ mediated genome instability 1 18 0.743 0.308 3.7E-06 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7702
Gene Symbol: ZNF143
ZNF143
P52747 zinc finger protein 143 39 0.670 0.577 2.4E-04 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7161
Gene Symbol: TP73
TP73
O15350 tumor protein p73 Transcription factor 300 0.449 0.808 1.00 0.010 None 1.000 1 0 2000 2000
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.010 None 1.000 1 0 2000 2000
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.010 None 1.000 1 0 2017 2017