Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.100 None 1.000 2 1 2018 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.100 None 1.000 1 1 2019 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.100 None 1.000 1 1 2018 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 1.000 3 4 2017 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 1.000 1 2 2017 2017
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 1.000 2 1 2019 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.100 None 1.000 1 1 2019 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 1.000 7 4 2009 2018
Entrez Id: 183
Gene Symbol: AGT
AGT 		P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.100 None 1.000 5 4 2016 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1 		P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.100 None 1.000 3 2 2017 2019
Entrez Id: 5972
Gene Symbol: REN
REN 		P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.100 None 1.000 1 1 2019 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.100 None 1.000 6 2 2016 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.100 None 1.000 1 1 2019 2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.100 None 1.000 1 1 2019 2019
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.100 None 1.000 1 1 2018 2018
Entrez Id: 4803
Gene Symbol: NGF
NGF 		P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.100 None 1.000 2 2 2017 2019
Entrez Id: 2200
Gene Symbol: FBN1
FBN1 		P35555 fibrillin 1 Calcium-binding protein 552 0.417 0.846 1.00 0.100 None 1.000 3 5 2017 2019
Entrez Id: 1398
Gene Symbol: CRK
CRK 		P46108 CRK proto-oncogene, adaptor protein 544 0.394 0.923 0.96 0.100 None 1.000 3 2 2017 2019
Entrez Id: 238
Gene Symbol: ALK
ALK 		Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.100 None 1.000 1 1 2016 2016
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1 		P26358 DNA methyltransferase 1 Epigenetic regulator 496 0.406 0.885 1.00 0.100 None 1.000 2 2 2019 2019
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		P01009 serpin family A member 1 Enzyme modulator 482 0.410 0.923 6.8E-08 0.100 None 1.000 1 1 2019 2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.100 None 1.000 1 1 2019 2019
Entrez Id: 6857
Gene Symbol: SYT1
SYT1 		P21579 synaptotagmin 1 Transporter 460 0.412 0.846 0.60 0.100 None 1.000 2 2 2018 2019
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2 		O15123 angiopoietin 2 Signaling 457 0.410 0.846 0.83 0.100 None 1.000 1 1 2019 2019
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B 		P46527 cyclin dependent kinase inhibitor 1B 454 0.409 0.769 0.62 0.100 None 1.000 1 1 2018 2018