Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.310 None 1.000 2 0 2001 2017
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.300 None 1.000 4 0 2003 2007
Entrez Id: 718
Gene Symbol: C3
C3
P01024 complement C3 Enzyme modulator 343 0.445 0.885 0.90 0.300 None 1.000 1 0 2013 2013
Entrez Id: 27429
Gene Symbol: HTRA2
HTRA2
O43464 HtrA serine peptidase 2 151 0.542 0.692 3.6E-03 0.300 None 1.000 1 0 2004 2004
Entrez Id: 842
Gene Symbol: CASP9
CASP9
P55211 caspase 9 Enzyme 293 0.458 0.808 7.4E-06 0.300 None 1.000 1 0 2001 2001
Entrez Id: 54205
Gene Symbol: CYCS
CYCS
P99999 cytochrome c, somatic 67 0.599 0.769 0.64 0.300 None 1.000 1 0 2001 2001
Entrez Id: 3611
Gene Symbol: ILK
ILK
Q13418 integrin linked kinase Kinase 192 0.503 0.769 3.8E-05 0.300 None 1.000 1 0 2004 2004
Entrez Id: 57447
Gene Symbol: NDRG2
NDRG2
Q9UN36 NDRG family member 2 Enzyme 156 0.518 0.692 2.2E-05 0.300 None 1.000 1 0 2013 2013
Entrez Id: 572
Gene Symbol: BAD
BAD
Q92934 BCL2 associated agonist of cell death 125 0.553 0.769 4.6E-03 0.300 None 1.000 1 0 2003 2003
Entrez Id: 134
Gene Symbol: ADORA1
ADORA1
P30542 adenosine A1 receptor G-protein coupled receptor 121 0.578 0.692 1.5E-02 0.300 None 1.000 1 0 2013 2013
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
Q9UM47 notch receptor 3 418 0.435 0.808 0.41 0.120 None 1.000 2 2 2001 2018
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.050 None 1.000 5 0 2018 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.050 None 1.000 5 0 2018 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.040 None 1.000 4 2 1998 2012
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.030 None 1.000 3 0 2017 2018
Entrez Id: 225
Gene Symbol: ABCD2
ABCD2
Q9UBJ2 ATP binding cassette subfamily D member 2 Transporter 25 0.711 0.500 4.7E-06 0.030 None 1.000 3 0 2017 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.020 None 1.000 2 0 2003 2004
Entrez Id: 1508
Gene Symbol: CTSB
CTSB
P07858 cathepsin B Enzyme 304 0.457 0.846 5.9E-11 0.020 None 1.000 2 0 2018 2018
Entrez Id: 8864
Gene Symbol: PER2
PER2
O15055 period circadian regulator 2 Transcription factor 238 0.488 0.846 0.71 0.020 None 1.000 2 0 2018 2018
Entrez Id: 5825
Gene Symbol: ABCD3
ABCD3
P28288 ATP binding cassette subfamily D member 3 Transporter 23 0.751 0.423 7.8E-03 0.020 None 1.000 2 0 2017 2019
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
P49841 glycogen synthase kinase 3 beta Kinase 393 0.430 0.846 0.96 0.020 None 1.000 2 0 2017 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.020 None 1.000 2 0 2007 2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.020 None 1.000 2 0 2019 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.020 None 1.000 2 0 2007 2011
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2019 2019