Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.400 None 0.974 77 1 1990 2020
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.390 None 1.000 11 0 1995 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.370 None 1.000 7 0 2006 2017
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.340 None 1.000 5 0 2004 2017
Entrez Id: 5268
Gene Symbol: SERPINB5
SERPINB5
P36952 serpin family B member 5 Enzyme modulator 87 0.582 0.577 3.6E-03 0.310 None 1.000 2 0 2010 2011
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.310 None 1.000 2 0 2014 2016
Entrez Id: 573
Gene Symbol: BAG1
BAG1
Q99933 BAG cochaperone 1 128 0.538 0.769 6.5E-06 0.310 None 1.000 1 0 2009 2009
Entrez Id: 1364
Gene Symbol: CLDN4
CLDN4
O14493 claudin 4 Cell-cell junction 164 0.514 0.692 7.0E-05 0.300 None 1.000 1 0 2009 2009
Entrez Id: 9368
Gene Symbol: SLC9A3R1
SLC9A3R1
O14745 SLC9A3 regulator 1 116 0.547 0.577 8.8E-05 0.300 None 1.000 1 0 2017 2017
Entrez Id: 5731
Gene Symbol: PTGER1
PTGER1
P34995 prostaglandin E receptor 1 G-protein coupled receptor 44 0.674 0.538 9.7E-04 0.300 None 1.000 1 0 2001 2001
Entrez Id: 468
Gene Symbol: ATF4
ATF4
P18848 activating transcription factor 4 178 0.507 0.769 1.6E-02 0.300 None 1.000 1 0 2004 2004
Entrez Id: 7009
Gene Symbol: TMBIM6
TMBIM6
P55061 transmembrane BAX inhibitor motif containing 6 52 0.653 0.577 1.5E-02 0.200 None 1.000 1 0 2006 2006
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.150 None 0.833 6 2 2000 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.130 None 1.000 4 2 2000 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 0.926 27 0 1997 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 1.000 18 0 1993 2019
Entrez Id: 5241
Gene Symbol: PGR
PGR
P06401 progesterone receptor Nuclear receptor 392 0.426 0.885 5.1E-02 0.100 None 0.769 13 0 1992 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 1.000 11 0 2017 2019
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 824 0.384 0.885 1.00 0.100 None 0.818 11 0 1997 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.090 None 0.889 9 0 1995 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.080 None 0.750 8 0 1990 2018
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.050 None 1.000 5 1 2011 2017
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.050 None 1.000 5 0 1996 2013
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.050 None 1.000 5 0 2004 2018
Entrez Id: 116150
Gene Symbol: NUS1
NUS1
Q96E22 NUS1 dehydrodolichyl diphosphate synthase subunit 94 0.619 0.615 0.98 0.040 None 1.000 4 0 2014 2019