Entrez Id: |
1499 |
Gene Symbol: |
CTNNB1 |
CTNNB1
|
P35222
|
catenin beta 1
|
|
412
|
0.417 |
0.759 |
1.00 |
0.810 |
|
1.000 |
3
|
3
|
1999 |
2014 |
Entrez Id: |
672 |
Gene Symbol: |
BRCA1 |
BRCA1
|
P38398
|
BRCA1, DNA repair associated
|
ligase
|
411
|
0.410 |
0.862 |
1.8E-28 |
0.800 |
strong
|
0.947 |
1491
|
34
|
1992 |
2018 |
Entrez Id: |
675 |
Gene Symbol: |
BRCA2 |
BRCA2
|
P51587
|
BRCA2, DNA repair associated
|
nucleic acid binding
|
358
|
0.426 |
0.793 |
5.5E-24 |
0.800 |
strong
|
0.945 |
641
|
12
|
1994 |
2018 |
Entrez Id: |
5889 |
Gene Symbol: |
RAD51C |
RAD51C
|
O43502
|
RAD51 paralog C
|
|
80
|
0.614 |
0.517 |
1.1E-13 |
0.800 |
definitive
|
0.966 |
31
|
4
|
2010 |
2018 |
Entrez Id: |
5892 |
Gene Symbol: |
RAD51D |
RAD51D
|
O75771
|
RAD51 paralog D
|
|
23
|
0.707 |
0.310 |
1.0E-08 |
0.800 |
definitive
|
1.000 |
17
|
3
|
2000 |
2017 |
Entrez Id: |
83990 |
Gene Symbol: |
BRIP1 |
BRIP1
|
Q9BX63
|
BRCA1 interacting protein C-terminal helicase 1
|
nucleic acid binding
|
89
|
0.586 |
0.552 |
4.8E-17 |
0.760 |
definitive
|
1.000 |
17
|
2
|
2001 |
2018 |
Entrez Id: |
7157 |
Gene Symbol: |
TP53 |
TP53
|
P04637
|
tumor protein p53
|
transcription factor
|
1773
|
0.251 |
0.897 |
0.17 |
0.700 |
limited
|
0.941 |
240
|
3
|
1991 |
2018 |
Entrez Id: |
2064 |
Gene Symbol: |
ERBB2 |
ERBB2
|
P04626
|
erb-b2 receptor tyrosine kinase 2
|
|
650
|
0.352 |
0.862 |
1.8E-03 |
0.700 |
|
0.973 |
153
|
3
|
1989 |
2018 |
Entrez Id: |
5290 |
Gene Symbol: |
PIK3CA |
PIK3CA
|
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
kinase; transferase
|
835
|
0.341 |
0.897 |
1.00 |
0.700 |
|
0.962 |
78
|
3
|
1999 |
2018 |
Entrez Id: |
5728 |
Gene Symbol: |
PTEN |
PTEN
|
P60484
|
phosphatase and tensin homolog
|
hydrolase; phosphatase
|
915
|
0.334 |
0.828 |
0.82 |
0.700 |
|
0.933 |
31
|
1
|
1998 |
2018 |
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
P40692
|
mutL homolog 1
|
nucleic acid binding
|
356
|
0.424 |
0.759 |
5.1E-05 |
0.700 |
strong
|
1.000 |
25
|
2
|
1995 |
2016 |
Entrez Id: |
580 |
Gene Symbol: |
BARD1 |
BARD1
|
Q99728
|
BRCA1 associated RING domain 1
|
|
54
|
0.624 |
0.379 |
2.2E-24 |
0.700 |
limited
|
0.857 |
23
|
1
|
1997 |
2018 |
Entrez Id: |
4436 |
Gene Symbol: |
MSH2 |
MSH2
|
P43246
|
mutS homolog 2
|
nucleic acid binding
|
320
|
0.437 |
0.690 |
0.91 |
0.700 |
strong
|
0.941 |
18
|
1
|
1994 |
2014 |
Entrez Id: |
79728 |
Gene Symbol: |
PALB2 |
PALB2
|
Q86YC2
|
partner and localizer of BRCA2
|
|
122
|
0.569 |
0.552 |
7.3E-20 |
0.680 |
moderate
|
0.750 |
11
|
2
|
2006 |
2016 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
O96017
|
checkpoint kinase 2
|
|
195
|
0.494 |
0.621 |
1.2E-23 |
0.660 |
disputed
|
0.833 |
10
|
4
|
2000 |
2016 |
Entrez Id: |
5395 |
Gene Symbol: |
PMS2 |
PMS2
|
P54278
|
PMS1 homolog 2, mismatch repair system component
|
nucleic acid binding
|
154
|
0.526 |
0.586 |
1.2E-27 |
0.650 |
strong
|
1.000 |
5
|
2
|
2006 |
2016 |
Entrez Id: |
4978 |
Gene Symbol: |
OPCML |
OPCML
|
Q14982
|
opioid binding protein/cell adhesion molecule like
|
|
36
|
0.663 |
0.517 |
0.25 |
0.630 |
|
1.000 |
3
|
1
|
2003 |
2014 |
Entrez Id: |
207 |
Gene Symbol: |
AKT1 |
AKT1
|
P31749
|
AKT serine/threonine kinase 1
|
calcium-binding protein; kinase; transfer/carrier protein; transferase
|
760
|
0.355 |
0.862 |
0.98 |
0.600 |
|
0.977 |
44
|
1
|
1997 |
2016 |
Entrez Id: |
3845 |
Gene Symbol: |
KRAS |
KRAS
|
P01116
|
KRAS proto-oncogene, GTPase
|
enzyme modulator
|
886
|
0.350 |
0.724 |
9.0E-04 |
0.600 |
|
0.882 |
18
|
1
|
1997 |
2017 |
Entrez Id: |
673 |
Gene Symbol: |
BRAF |
BRAF
|
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
|
871
|
0.352 |
0.793 |
1.00 |
0.600 |
|
0.923 |
14
|
3
|
2002 |
2017 |
Entrez Id: |
898 |
Gene Symbol: |
CCNE1 |
CCNE1
|
P24864
|
cyclin E1
|
enzyme modulator
|
74
|
0.590 |
0.517 |
0.96 |
0.600 |
|
1.000 |
14
|
2
|
2008 |
2018 |
Entrez Id: |
4361 |
Gene Symbol: |
MRE11 |
MRE11
|
P49959
|
MRE11 homolog, double strand break repair nuclease
|
|
110
|
0.554 |
0.724 |
|
0.600 |
disputed
|
|
6
|
1
|
1998 |
2017 |
Entrez Id: |
472 |
Gene Symbol: |
ATM |
ATM
|
Q13315
|
ATM serine/threonine kinase
|
kinase; nucleic acid binding; transferase
|
486
|
0.401 |
0.862 |
6.0E-46 |
0.570 |
limited
|
1.000 |
11
|
1
|
1998 |
2018 |
Entrez Id: |
999 |
Gene Symbol: |
CDH1 |
CDH1
|
P12830
|
cadherin 1
|
|
322
|
0.432 |
0.759 |
0.11 |
0.550 |
|
1.000 |
6
|
0
|
1994 |
2016 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
P52701
|
mutS homolog 6
|
|
189
|
0.495 |
0.586 |
2.2E-05 |
0.550 |
strong
|
1.000 |
5
|
0
|
2006 |
2015 |