Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.330 None 1.000 4 0 2007 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 270 0.248 0.962 0.32 0.300 None 1.000 1 0 1995 1995
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.310 None 1.000 1 0 2013 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.320 None 1.000 1 0 2001 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.300 None 1.000 1 0 2002 2002
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.310 None 1.000 1 0 2000 2010
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 68 0.343 0.885 1.00 0.300 None 1.000 1 0 2013 2013
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 241 0.356 0.846 1.2E-04 0.300 None 1.000 1 0 1988 1988
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 66 0.376 0.885 4.6E-09 0.300 None 1.000 1 0 2018 2018
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.300 None 1.000 1 0 2004 2004
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 61 0.380 0.923 2.1E-03 0.300 None 1.000 2 0 2008 2015
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 90 0.380 0.846 0.97 0.300 None 1.000 1 0 2015 2015
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 103 0.383 0.923 1.4E-02 0.300 None 1.000 1 0 2004 2004
Entrez Id: 3596
Gene Symbol: IL13
IL13
P35225 interleukin 13 34 0.386 0.846 1.4E-02 0.300 None 1.000 1 0 2012 2012
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
P11166 solute carrier family 2 member 1 Transporter 94 0.388 0.808 0.99 0.310 None 1.000 1 0 1994 2011
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 52 0.393 0.923 1.5E-04 0.300 None 1.000 2 0 2008 2015
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 45 0.396 0.846 3.2E-06 0.300 None 1.000 1 0 2012 2012
Entrez Id: 5970
Gene Symbol: RELA
RELA
Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 63 0.406 0.885 1.00 0.300 None 1.000 1 0 2007 2007
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 Signaling 49 0.413 0.885 0.13 0.300 None 1.000 1 0 2010 2010
Entrez Id: 2321
Gene Symbol: FLT1
FLT1
P17948 fms related receptor tyrosine kinase 1 Kinase 39 0.419 0.846 1.00 0.300 None 1.000 1 0 2006 2006
Entrez Id: 353
Gene Symbol: APRT
APRT
P07741 adenine phosphoribosyltransferase 21 0.423 0.846 5.5E-13 0.300 None 1.000 1 0 2004 2004
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 28 0.424 0.846 1.00 0.300 None 1.000 2 0 2011 2013
Entrez Id: 3329
Gene Symbol: HSPD1
HSPD1
P10809 heat shock protein family D (Hsp60) member 1 35 0.432 0.808 0.99 0.300 None 1.000 1 0 2004 2004
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
P04792 heat shock protein family B (small) member 1 47 0.436 0.808 2.8E-07 0.300 None 1.000 1 0 2004 2004
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 74 0.440 0.808 1.00 0.300 None 1.000 1 0 2011 2011