Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.100 None 0.960 175 0 1998 2020
Entrez Id: 2335
Gene Symbol: FN1
FN1 		P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.100 None 0.975 162 1 1990 2020
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.100 None 0.975 159 0 1994 2020
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1 		P37275 zinc finger E-box binding homeobox 1 Transcription factor 310 0.442 0.808 0.97 0.100 None 1.000 156 1 2005 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.100 None 0.994 155 3 1997 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 0.981 154 0 1993 2020
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2 		P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.100 None 1.000 148 1 2002 2020
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3 		P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.100 None 0.993 140 0 2002 2020
Entrez Id: 5879
Gene Symbol: RAC1
RAC1 		P63000 Rac family small GTPase 1 Enzyme modulator 415 0.429 0.962 0.76 0.100 None 0.979 140 0 2000 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.100 None 0.986 138 0 1995 2020
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12 		P48061 C-X-C motif chemokine ligand 12 626 0.379 0.846 0.12 0.100 None 0.977 131 0 2004 2020
Entrez Id: 682
Gene Symbol: BSG
BSG 		P35613 basigin (Ok blood group) 287 0.458 0.769 2.6E-05 0.100 None 0.992 127 0 1993 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.984 126 0 1993 2020
Entrez Id: 406937
Gene Symbol: MIR145
MIR145 		microRNA 145 366 0.431 0.846 0.100 None 0.992 122 0 2010 2019
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.100 None 0.983 118 2 1996 2020
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.100 None 0.991 116 0 2003 2020
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.100 None 0.983 115 0 1993 2020
Entrez Id: 5340
Gene Symbol: PLG
PLG 		P00747 plasminogen Enzyme 586 0.389 0.923 1.0E-02 0.100 None 1.000 113 0 1983 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 0.972 108 1 1990 2019
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1 		Q15672 twist family bHLH transcription factor 1 Transcription factor 559 0.397 0.846 0.34 0.100 None 0.991 107 0 2005 2019
Entrez Id: 4316
Gene Symbol: MMP7
MMP7 		P09237 matrix metallopeptidase 7 Enzyme 320 0.446 0.885 1.0E-09 0.100 None 1.000 106 1 1993 2019
Entrez Id: 174
Gene Symbol: AFP
AFP 		P02771 alpha fetoprotein Transporter 392 0.429 0.885 1.1E-11 0.100 None 0.950 101 2 1995 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.100 None 0.990 101 0 1997 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.100 None 0.970 101 2 2004 2020
Entrez Id: 10855
Gene Symbol: HPSE
HPSE 		Q9Y251 heparanase Enzyme 393 0.425 0.808 2.3E-14 0.100 None 0.980 100 2 1997 2019